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Biomedical subjects

G Santosa

Publications and source records attributed to G Santosa.

7 recordsLinked to original sources

Microbiology of chronic suppurative otitis media in children in Surabaya, Indonesia.

The aerobic and anaerobic microbiology of 38 children from Surabaya, Indonesia, who suffered from chronic suppurative otitis media (CSOM) was studied using strict microbiological methodology. A total of 106 isolates (49 anaerobic and 57 aerobic) were recovered. Aerobic organisms alone were isolated from 11 (29%), anaerobic bacteria only in 4 (11%) and mixed aerobic and anaerobic flora were present in 23 (60%). The predominant organisms were Peptostreptococcus sp., Prevotella sp., Bacteroides sp., Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae and Fusobacterium sp. Thirty-nine beta-lactamase-producing bacteria were recovered from 22 (58%) patients. These findings demonstrate the role of penicillin resistant aerobic and anaerobic bacteria in the polymicrobial etiology of CSOM in children from Indonesia. Judicious use of antimicrobial therapy may prevent the development of antimicrobial resistance.

Adolescent↗

The predictive value of Phadiatop Paediatric in the determination of atopy in allergic diseases in children.

We obtained 28 patients with asthma bronchiale in this study. The presumptive diagnosis of allergy was made on the basis of history and physical examination. The positive result of the skin test to inhalant extracts and positive history of inhalant allergy add a confirmatory evidence in the diagnosis of inhalant allergy. The diagnosis of food allergy was judged by positive result in the provocation test. This study provided 15 patients with food allergy and 13 patients with food and inhalant allergy. House dust and mites were the most prevalent positive result in the skin test. While in the provocation test, egg and milk were found as the most prevalent food causing symptoms of allergy. The skin test predicted the atopy with an efficiency of 53.5%, while Phadiatop Paediatric predicted the atopy with an efficiency of 82.1%. We concluded, as a screening procedure in allergy, the Phadiatop Paediatric is better than the skin test. Nevertheless the skin test has its superiority in the development of logical environmental controls and as a guide to immunotherapy in inhalant allergy.

Antibodies, Anti-Idiotypic↗

Acute mediastinitis.

Mediastinitis is not a new disease, however, the occurrence was rare especially in children. Focal infection, which considered to be insignificant, can result in diffuse dissemination involving mediastinum leading to fatal condition. This paper reported a case of mediastinitis with very critical condition. Fast and accurate diagnosis as well as adequate antibiotic treatment saved the patient without surgical intervention.

Cefotaxime↗