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Biomedical subjects

G Sangster

Publications and source records attributed to G Sangster.

31 records · Page 2Linked to original sources
PubMed1981

Medically serious self-poisoning in West Fife, 1970-1979.

Two thousand two hundred and four patients with acute poisoning admitted between 1970 and 1979 to an acute District Medical Unit were reviewed with special regard to the serious medical consequences of overdosage. The incidence of barbiturate and methaqualone poisonings declined but benzodiazepines, tricyclic antidepressants, and dextroproproxyphene were more commonly taken. As a result, there was no overall change in the proportion of patients admitted unconscious or requiring respiratory support. The dangers of dextropropoxyphene poisoning have become increasingly apparent, and poisoning with paracetamol has become as frequent as salicylate poisoning. In view of these changing trends, measures to limit the morbidity and mortality from self-poisoning are suggested.

Adult↗
PubMed1978

The effects of pre-admission antibiotics on the bacteriological diagnosis of pyogenic meningitis.

To assess the effects of pre-admission antibiotics on the accuracy of bacterial diagnosis in pyogenic meningitis, the case records of 154 patients admitted to an infectious diseases unit during a 10-year period (1966-1975) were reviewed. The causative organism was identified in 140 patients (91%). Although 63 patients had received antibiotics before admission, a bacteriological diagnosis was still possible in 57 of these (90%).

Adolescent↗
PubMedDate not supplied

An immunohistochemical and clinicopathological study of granulocytic sarcoma ('chloroma').

A small series of granulocytic sarcomas (GS) or 'chloromas' has been studied by means of conventional histology and immunohistochemistry. The latter was found to be most useful in the diagnosis and characterization of these neoplasms, which are rare in Great Britain. Polytypic antisera to leukocyte elastase and cathepsin G have proved to be most useful, giving intense staining in all cases. These two markers are more specific than muramidase (lysozyme) and alpha 1-antitrypsin, since, unlike the latter two, they do not stain histiocytic cells. The results of staining with two monoclonal antisera, AGF 4.48 and AGF 4.36, are also described. In addition, the clinicopathological details of the seven cases are summarized and the literature is briefly surveyed.

Adult↗