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Biomedical subjects

G Sandini

Publications and source records attributed to G Sandini.

16 recordsLinked to original sources
PubMed1999

A developmental approach to visually-guided reaching in artificial systems.

The aim of the present paper is to propose that the adoption of a framework of biological development is suitable for the construction of artificial systems. We will argue that a developmental approach does provide unique insights on how to build highly complex and adaptable artificial systems. To illustrate our point, we will use as an example the acquisition of goal-directed reaching. In the initial part of the paper we will outline (a) how mechanisms of biological development can be adapted to the artificial world, and (b) how this artificial development differs from traditional engineering approaches to robotics. An experiment performed on an artificial system initially controlled by motor reflexes is presented, showing the acquisition of visuo-motor maps for ballistic control of reaching without explicit knowledge of the system's kinematic parameters.

Journal Article↗
PubMed1997

New developments in low-bit rate videotelephony for people who are deaf.

This study was designed to evaluate the picture quality requirements for three visual communication modes: speechreading, fingerspelling, and sign language. Video recordings of everyday spoken, fingerspelled, and signed sentences were made, and some recordings were processed using a computer simulation of the IBIDEM technology: a videophone based on a novel type of visual sensor. This retina-like sensor, implemented in the camera, has a high resolution in the central part and a degrading resolution in the peripheral part of the picture. Two independent variables were examined: frame rate (10 and 15 frames per second) and spatial resolution (6000 and 8000 pixels per frame). Twenty-four people who were prelingually deaf participated, 8 in each communication mode. The results showed a marked effect of frame rate on speechreading. Fingerspelling and sign language were not affected by frame rate, and spatial resolution had no effect on any of the three communication modes.

Adolescent↗
PubMed1996

The AGROBOT project.

The aim of this paper is to illustrate the AGROBOT project. This project was initiated to develop a complete robotic system for the production cycle of tomato plants in a greenhouse environment. The robot architecture is based on a vehicle carrying the picking arm (a six degrees of freedom anthropomorphic arm with a gripper/hand), the head with the two micro cameras (for the color stereoscopic vision system) and the VME rack for the complete control of the system. The head was purposely developed to permit complete visibility of the overall area. The vision system drives the head to point the path during navigation or to explore the plants looking for the work objects. The robot will be able to navigate between rows of plants, stop near each plant and identify the relevant objects (fruits or flowers) so as to be able to pick ripe tomatoes or spray anticryptogamic substances on flowers. Due to its flexible architecture, the system can be suited to operate on other kinds of cultivation or could be modified to perform other kinds of operations such as transplanting or packaging. Also the field of action could be different from greenhouses: changing from a wheeled locomotion system to a tracked system, the robot will be able to operate on particularly irregular surfaces. These features make this robotic system particularly adapted to replace human from tiring and harmful tasks or operating within adverse environment.

Agriculture↗
PubMed1984

Development of retinal acuity in infants evaluated with pattern electroretinogram.

The electroretinographic (ERG) response to patterns of constant mean luminance (sinusoidal gratings reversed in contrast at 12 rev/s) has been recorded in infants 7 weeks to 6 months old. At each age the amplitude of the ERG for relatively fine gratings decreases with increasing spatial frequency and vanishes for a spatial frequency that can be defined as ERG acuity. It has been found that ERG acuity increases progressively with age. The acuity evaluated from cortical evoked potentials (VEP) recorded simultaneously with the ERG increases with age in parallel with ERG acuity. These findings are in agreement with data reported in the literature for the cat, indicating a parallel postnatal development of acuity at a retinal and cortical level.

Electroretinography↗
PubMed1983

Visual acuity in the young infant is highest in a small retinal area.

Visual potentials (VEP) evoked by alternating gratings were recorded daily in one infant between 10 and 13 weeks of age and at 20 weeks of age. The VEP amplitude was measured for a stimulus field of increasing area at low and high spatial frequencies. At low spatial frequencies the VEP amplitude increases with increasing stimulus area, while at high spatial frequencies (near visual acuity) the VEP amplitude remains constant for stimulus field sizes beyond 2 deg. These findings parallel those obtained in the adult, and indicate that visual acuity of the infant is not uniform across the retina but is highest in a small region, as in the adult.

Adult↗
PubMed1983

The role of high spatial frequencies in face perception.

The relevance of low and high spatial-frequency information for the recognition of photographs of faces has been investigated by testing recognition of faces that have been either low-pass (LP) or high-pass (HP) filtered in the spatial-frequency domain. The highest resolvable spatial frequency was set at 15 cycles per face width (cycles fw-1). Recognition was much less accurate for images that contained only the low spatial frequencies (up to 5 cycles fw-1) than for images that contained only spatial frequencies higher than 5 cycles fw-1. For faces HP filtered above 8 cycles fw-1, recognition was almost as accurate as for faces LP filtered below 8 cycles fw-1, although the energy content of the latter greatly exceeded that of the former. These findings show that information conveyed by the higher spatial frequencies is not redundant. Rather, it is sufficient by itself to ensure recognition.

Discrimination, Psychological↗
PubMed1983

Topography of brain electrical activity: a bioengineering approach.

The aim of this work is to describe a system for the mono- and bi-dimensional analysis of brain electrical activity. The analysis was carried on either by visual inspection of mono- and bi-dimensional data, or by automatic feature extraction from the bidimensional data. Because of the importance of visual inspection for the analysis of experimental data, particular care was devoted to optimize the displayed data perceptually. For automatic screening of large amounts of data (and to allow long term studies of clinical records), statistical facilities were also provided. One purpose of the system was to develop image processing algorithms oriented toward biomedical images, that could be easily implemented on special purpose, low cost hardware, like VLSI or microcomputer arrays. This was possible because of the modularity of the larger part of bidimensional processing, such as interpolation and statistical analysis. Results of an experiment on Visual Evoked Response are presented, showing that through abidimensional analysis of the recorded data the resolution achievable in the localization of brain electrical activity can be increased to less than 1 cm.

Brain↗
PubMed1982

A model of the early stages of the human visual system: functional and topological transformations performed in the peripheral visual field.

A model of the early stages of the visual system is presented, with particular reference to the region of the visual field outside the fovea and to the class of retinal and lateral geniculate nucleus cells which are most active in the processing of patter information (X-cells). The main neuroanatomical and neurophysiological properties taken into account are: the linear increase of the receptive fields diameter with eccentricity, the constancy of the overlap factor and the topological transformation operated upon the retinal image by the retino-cortical connection. The type of filtering taking place between the retina and the visual cortex is analyzed and some simulations are presented. It is shown that such a filtering is of a bandpass space variant type, with center frequencies that decrease from the center (i.e. the fovea) toward the periphery of the visual field. This processing is "form invariant" under linear scaling of the input. Moreover, considering the properties of the retino-cortical connection, it is shown that the "cortical images" undergo simple shifts whenever the retinal images are scaled or rotated.

Humans↗
PubMed1980

Dyslexia: regional differences in brain electrical activity by topographic mapping.

Electroencephalographic (EEG) and evoked potential data were recorded during behavioral testing from 8 dyslexic and 10 normal boys aged 9 to 11 years. Topographic mapping of their brain electrical activity revealed four discrete regions of difference between the two groups involving both hemispheres, left more than right. Aberrant dyslexic physiology was not restricted to a single locus but was found in much of the cortical region ordinarily involved in reading and speech. Prominent group differences were observed in the bifrontal area in addition to the more expected left temporal and left posterior quadrant regions. Although activation tests produced more prominent group difference, dyslexics differed from normal subjects at rest as well. EEG alpha activity was increased for the dyslexics, suggesting relative cortical inactivity in that group.

Alpha Rhythm↗
PubMed1980

Dyslexia: automated diagnosis by computerized classification of brain electrical activity.

We describe a method for the diagnosis of dyslexia based upon a study of electroencephalographic and evoked potential data recorded from 13 normal and 11 dyslexic boys. Measurements were made from topographic maps of brain electrical activity recorded during resting and activated testing conditions. Using a statistically based technique, we developed rules for classification that successfully diagnosed 80 to 90% of subjects not used in the initial rule development. The nature of the most useful measurements suggests that aberrant neurophysiology in dyslexia involves both hemispheres and is present at rest as well as during complex testing. The method has promise for future diagnosis and research.

Alpha Rhythm↗
PubMed1979

A perceptual phenomenon and its neurophysiological correlate.

A square-wave grating from which the fundamental harmonic has been subtracted (missing fundamental grating) when viewed from a suitable distance appears similar to another grating of periodicity three times higher. The neurons of the visual cortex of the cat, in a given range of spatial frequencies characteristic of each cell, give similar responses to the two gratings.

Animals↗
PubMed1979

Responses of visual cortical cells to periodic and non-periodic stimuli.

1. The activity of neurones of the visual cortex (area 17) has been recorded in anaesthetized cats in response to gratings of different profile and to single light and dark bars. 2. At very low spatial frequencies, outside the frequency response range to sinusoidal gratings, the response to square-wave drifting gratings is obtainable from a combination of the response to the single bars of the grating presented in isolation. At higher spatial frequencies this is no longer true. 3. At very low spatial frequencies the responses to square-wave gratings and to missing-fundamental gratings (obtained by subtraction from the square-wave grating of its fundamental gratings (obtained by subtraction from the square-wave grating of its fundamental harmonic) are very similar. 4. At spatial frequencies near the peak of the spatial frequency tuning curve of the cell, the responses to square-wave grating and to sinusoidal gratings are very similar. At these spatial frequencies the response to the missing-fundamental grating is practically zero. 5. At spatial frequencies lower than that of best sensitivity for the cell, the response to square-wave gratings is correlated with the 1st and 3rd harmonic of the stimulus. 6. We conclude that at very low spatial frequencies of the grating the response of cortical cells is correlated with the light or dark edges (or light or dark bars) of the stimulus, because the edges contain high frequencies within the range of sensitivity of the cells. At higher spatial frequencies the results are interpreted best by assuming that cortical cells respond to the harmonics of the visual periodic stimulus. 7. When a background of dynamic visual noise is added to increase the spontaneous discharge of simple cells, their response to visual stimuli becomes linear or quasi-linear. The stimuli could be either single bars or gratings.

Action Potentials↗
PubMedDate not supplied

Regional cerebral blood flow in essential hypertension: data evaluation by a mapping system.

Regional cerebral blood flow was studied by means of the 133Xe inhalation method in 26 untreated and 10 treated patients with essential hypertension. The untreated subjects were divided into newly and previously diagnosed groups to assess the relation between regional cerebral blood flow and the duration of hypertension. The overall flow reduction was more marked in the frontal and temporal regions in the previously diagnosed group, and this was attributed to pathological changes in the district served by the middle cerebral artery. Regional temporal lobe impairment was also noted in the newly diagnosed and treated subjects. A significant correlation was found between regional cerebral blood flow and mean arterial blood pressure.

Aged↗