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Biomedical subjects

G Samuel

Publications and source records attributed to G Samuel.

24 records · Page 2Linked to original sources
PubMed1983

Solid-phase radioimmunoassay for human placental lactogen in serum.

We report a solid-phase radioimmunoassay for human placental lactogen, in which antibody-coated polystyrene tubes and polyurethane sponges are used. Incubation time and temperature, ionic strength of buffer, and nonspecific adsorption have been evaluated for optimum conditions required for routine clinical assays. The validity of the assay technique has been ascertained by its specificity, reproducibility, and recovery. The sensitivity of this method is 0.4 ng of placental lactogen per assay tube.

Female↗
PubMed1975

Paratenuisentis gen. n. for Tanaorhamphus ambiguus Van Cleave 1921 (Acanthocephala), with a reconsideration of the Tenuisentidae.

Paratenuisentis gen. n. (Tenuisentidae) is characterized by quincuncially arranged proboscis hooks, numerous giant nuclei in the subcuticula and cement glands, and a prominent muscular sling around the proboscis receptacle. P. ambiguus (Van Cleave, 1921) is redescribed following study of a long series of mature males and females. On the basis of the typical pattern of giant nuclei distribution, it is concluded that Tanaorhamphus and Microsentis, previously included in the Tenuisentidae, belong in the Neoechinrhynchidae.

Acanthocephala↗
PubMedDate not supplied

Conservation of a DPP/BMP signaling pathway in the nonbilateral cnidarian Acropora millepora.

Members of the TGF-beta superfamily of signaling molecules are widespread in metazoans, but the evolutionary origin of particular subclasses of signaling mechanisms is poorly defined. The DPP/BMP class, for example, is implicated in dorsal-ventral patterning, neural patterning, and limb development. Here we report the presence of several components of a DPP/BMP-specific signal transduction cascade in a nonbilateral animal, the coral Acropora millepora. The discovery of these components, a putative type I receptor and two putative receptor-activated Smads, suggests that DPP/BMP signaling predates both dorsal-ventral pattern formation and limb development. We postulate that an ancestral role in neuroepithelial patterning may account for the high level of conservation between DPP/BMP signaling components found in this nonbilateral animal and the more complex triploblastic organisms of the arthropod and chordate phyla.

Amino Acid Sequence↗