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Biomedical subjects

G Sakimoto

Publications and source records attributed to G Sakimoto.

6 recordsLinked to original sources
PubMed1984

Decrease of anterior ciliary arterial pressure with increased ocular pressure.

The relationship of the ocular pressure to the anterior ciliary arterial pressure was studied by measuring the pressure of the anterior ciliary artery using a modified pressure chamber. Of the 40 subjects, 9 were normal, 16 were ocular hypertensive patients, and 15 were primary, open-angle, glaucoma patients. A significant negative correlation was found between the anterior ciliary arterial pressure and the ocular pressure such that the former decreases as the latter increases. These results support the concept that the blood flow in the anterior ciliary artery is from the inside of the eye to the outside.

Aged↗
PubMed1979

Effects of topically applied bupranolol on the intraocular pressure. Effects on the untreated eye.

Topically applied bupranolol, a beta-adrenergic blocking agent, has been shown to have a marked effectiveness in lowering the intraocular pressure of the normal and glaucomatous eyes. The effects were not only seen in the treated eyes but also in the untreated, contralateral eyes. The contralateral response was independent of the ongoing diurnal variation of the intraocular pressure. Instillation of the drug into the nasal cavity induced decrease of the intraocular pressure in both eyes, the extent of which was comparable to the contralateral response induced by ocular instillation. These observations suggest that the contralateral response is caused by systemically absorbed drug, probably due to the action on the central locus regulating the intraocular pressure. Instillation of pilocarpine did not show any similar contralateral response.

Absorption↗