Biomedical subjects
G Sacks
Publications and source records attributed to G Sacks.
An innate view of human pregnancy.
Our understanding of the immunology of pregnancy has been dominated by the fetal allograft model and by changes in the maternal-specific immune system. Here, Gavin Sacks and colleagues draw attention to substantial and contrasting changes in the maternal innate system and hypothesize that its function and that of monocytes in particular, has a central role in the maternal-fetal relationship.
Caesarean section: an evolving procedure?
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Evaluation of a practice-based programme of health checks: financial cost and success at risk detection.
With the help and supervision of a facilitator, a scheme of nurse-run health checks was established in 1983 in a suburban group practice of approximately 12,000 patients. The practice receptionists recruited patients opportunistically when they presented to consult a doctor. After two and a half years, 1382 patients had been screened for cardiovascular risk factors; this was 94.0% of those invited to attend and 24.9% of the target population of patients aged 25-64 years. Recording of risk factors increased greatly between 1983 and 1986, although uptake of immunizations was low. Sixty five previously undiagnosed hypertensives were identified, as were 11 new diabetics. This was achieved with two sessions per week; thus to succeed in screening the whole population within five years, four weekly sessions would have been necessary. When the cost of equipment and staff salaries were offset against 70% reimbursement of salaries and item of service fees the net financial cost to practice from 1983-86 was approximately 1.73 pounds per patient, or 477.00 pounds per clinic session per year.
The effects of alcohol on prose memory.
The present study examined the effects of acute alcoholic intoxication on prose memory. Intoxicated and sober subjects listened to six narrative passages at different presentation rates. Immediately after listening to a tape-recorded version of each story, subjects orally recalled it. The results demonstrated that sober subjects recalled more than intoxicated subjects, but subjects from both groups favored the main ideas in their recalls. However, at the fastest presentation rate, intoxicated subjects showed some diminished sensitivity to the semantic structure of prose. It was suggested that alcohol induced deficits in prose memory may result from a general slowing in the rate with which text is encoded into working memory.
Detection of metastatic liver disease with Tc-99m MAA during a thromboscintigram/lung scan.
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Scintigraphic and sonographic diagnosis of neonatal mesoblastic nephroma. Case report.
The morphologic characteristics of mesoblastic nephroma result in a scintigraphic appearance which distinguishes this benign neonatal tumor from Wilms' tumor. This case report describes a patient in whom the use of scintigraphy and real-time sonography permitted preoperative diagnosis of mesoblastic nephroma.
The CT detection of thymic hyperplasia in association with thyrotoxicosis: case report.
A thymic mass was diagnosed by computed tomography in a young male with an anterior mediastinal mass demonstrated by chest X-ray. The association of thymic hyperplasia and thyrotoxicosis is discussed and the importance of CT in the evaluation of anterior mediastinal masses in patients with thyrotoxicosis is emphasized. Micronodular enlargement of the thymus is a common association of Graves' disease in contradistinction to the rare detection of radiologically visible thymic masses in this condition.
Lymphangioma of the tongue and the team approach.
Case report of a 9-year-old female with a 7cm (length) x 4cm (width) x 1cm (thick) lymphangioma of the tongue. The tumor caused speech distortion, crowding of the anterior maxillary and mandibular teeth, and a prognathic mandible. The patient was evaluated by the members of the Cleft Lip and Palate Team at St. Christopher's Hospital and underwent a complete resection of the tumor and is continuing follow-up care. This case exemplifies the value in a team approach to a variety of intraoral problems.