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Biomedical subjects

G Sack

Publications and source records attributed to G Sack.

30 records · Page 2Linked to original sources
PubMed1977

[EEG studies of spinocerebellar ataxia].

Electroencephalographic examinations of eighteen patients with spinocerebellar ataxias and of thirteen normal sibs of four of the subjects are reported. The authors frequently observed low levels of potential and a tendency toward slackening in basic activity, which is in agreement with data presented in the literature; theta-delta inclusions in the temporal regions were found especially in cases of cerebellar ataxia. Examinations of the sib frequently showed low-potential curves. However, the use of electroencephalography for the purpose of identifying, in the case of hereditary ataxia, latently diseased sibs for heterozygous individuals does not seem possible.

Adolescent↗
PubMed1975

[Results of electroencephalographic and familial studies in Wilson's disease].

The results of electroencephalographic and familial studies of 31 Wilson's disease patients coming from 26 kindreds are presented. Prior to treatment, 8 patients showed pathological conditions, while 9 and 11 patients showed borderline and normal conditions, respectively, it having not been possible to determine electroencephalographic conditions characteristic of Wilson's disease and find any relationships between the intensity of E.E.G. changes and the clinical picture and stage of development of the disease, respectively. Under penicillamine treatment, there was observed a tendency toward normalization of pathological conditions rather than deterioration of normal E.E.G. findings. So far as familial studies are concerned, the authors report the results obtained for 9 fathers, 19 mothers, and 24 siblings from a total of 21 kindreds; what is remarkable in this connection is the comparatively small percentage of normal E.E.G. findings for healthy siblings. It was only in one single kindred that it was possible to observe similarities between E.E.G. variations of individual family members.

Adolescent↗