Biomedical subjects

G Sällsten

Publications and source records attributed to G Sällsten.

39 records · Page 3Linked to original sources

PubMed1981

Cancer morbidity among men exposed to oil mist in the metal industry.

The cancer morbidity pattern among 788 men with at least five years' exposure to oil mist was investigated. Based on measurements, interviews of workers and a survey of changes over the years, the average exposure level was estimated to have been 5 mg/m3 or more prior to 1965. Exclusive of cancer of the scrotum, there were 39 observed cases of cancer compared to 52.9 expected. There were four cases of cancer of the scrotum among the turners but none among the grinders. Three cases of lung cancer were found, compared to 5.4 expected. Among the grinders there was a doubled, but not statistically significant, increase in cancer of the stomach. The mortality from all causes showed a so-called "healthy worker effect," that is, 126 deaths compared to 154.3 expected.

Adult↗

PubMed1980

Method of the cohort study--a practical example.

The method is demonstrated in connection with a study of lung cancer among metal-workers exposed to oil mist. As exposure to oil mist is uncommon and lung cancer is common, the cohort study is the method of choice. Estimation of exposure, problems of selection, calculation of person-years etc is discussed. There was no increased morbidity from lung cancer.

Adult↗

PubMedDate not supplied

Kinetics of mercury in blood and urine after brief occupational exposure.

The decrease in mercury (Hg) levels in whole blood (B), plasma (P), erythrocytes (Ery), and urine (U) was investigated in nine men after 3 d of intense (greater than 100 micrograms/m3) exposure to metallic Hg vapor. In a model in which common half-times for all subjects were used, the best fit for B-Hg was obtained with half-times of 3.1 d for a fast phase and 18 d for a slow phase. P-Hg seemed to decay more rapidly than Ery-Hg. Peak U-Hg (morning, creatinine-corrected samples) was not observed until 2-3 wk after exposure. Thereafter, the median half-time was 40 d (assuming individual one-compartment models). In a model for which common half-times were used, the point estimates were 59 d for a one-compartment model and 28 and 141 d for a two-compartment model. The fractions of the fast phases (i.e., two-compartment models with common half-times) were 80% for B-Hg and 84% for U-Hg.

Environmental Monitoring↗