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Biomedical subjects

G Rothman

Publications and source records attributed to G Rothman.

9 recordsLinked to original sources

Unilateral choanal atresia masquerading as chronic sinusitis.

Choanal atresia is a congenital anomaly usually diagnosed at birth. This case involves bilateral choanal atresia in a newborn with respiratory difficulties in whom there is an inability to pass a #8 French catheter through the nose. In contrast, unilateral choanal atresia causes a variable degree of nasal obstruction that may delay the diagnosis. We report a case of unilateral choanal atresia in a 9-year-old boy diagnosed as having chronic sinusitis with allergic rhinitus. Initial interpretation of a computerized, tomographic (CT) examination confirmed the diagnosis of chronic sinusitis. The definitive diagnosis, however, was made by endoscopic evaluation. A review is presented of the epidemiology, clinical presentation, differential diagnosis, and contemporary surgical management for unilateral choanal atresia.

Child↗

Red blood cell membrane and serum sialic acid in relation to erythrocyte sedimentation rate.

Sialic acid was determined in red blood cell (RBC) membrane and in serum, and correlated to erythrocyte sedimentation rate (ESR). For this purpose blood samples were obtained from 57 patients, regardless of their pathological condition, and divided into groups according to the ESR. 15 blood samples obtained from health individuals whose ESR was lower than 20 mm/h served as controls. Sialic acid was released from RBC membranes obtained by hemolysis, and from serum glycoproteins precipitated with ethanol by treatment with 0.1 N HCl at 80 degrees C for 1 h. The results showed the sialic acid contents of both membranes and serum to be higher in most of the groups with elevated ESR, as compared to the control group, although no quantitative correlation was noticed. Statistical evaluation showed highly significant differences between the group of pathological samples as a whole and the control group in the sialic acid content of both RBC membranes and sera.

Blood Sedimentation↗