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Biomedical subjects

G Rosato

Publications and source records attributed to G Rosato.

10 recordsLinked to original sources

Subacute cardiac rupture complicating myocardial infarction. A case report.

The authors have focused this study on the emergence of subacute ventricular free wall rupture in a seventy-six-year-old patient admitted to hospital for inferior acute myocardial infarction. After six days he showed clinical signs of bradycardia and hypotension evolving to electromechanical dissociation. Given an adequate pharmacologic therapy, the patient was submitted to echocardiography, which was believed to be consistent with myocardial rupture, showing a moderate to large pericardial effusion. Pericardiocentesis of 150 mL of bloody fluid resulted in a further improvement in his hemodynamics. The patient underwent cardiac surgery with repair of the myocardial rupture through a large diaphragmatic infarction by a Dacron polyester fiber graft and pacemaker placement. In conclusion the authors confirm the relevant role of clinical data such as persistent chest pain and hemodynamic instability and the value of echocardiography in identifying subacute myocardial free wall rupture after an episode of acute myocardial infarction.

Aged

[Post-splenectomy hyperthermia].

After an examination of the most important physiopathological alterations of splenectomised patients and on the basis of careful research into the literature on study and classification of post-splenectomy hyperthermia, the Authors stress the importance of infections in the genesis of such hyperthermia, until a few years ago defined as "sine causa". On the basis of the consideration that this fever is due to an infection acting on an area (the a-splenic area) which is more vulnerable as it is deprived of a certain part of the reticulo-endothelial system, it was possible to postulate and verify that such hyperthermia could arise only in patients with altered extra-splenic reticulo-endothelial system and hence does not normally occur in patients splenectomised for trauma. On the basis of extensive personal experience, the authors conclude by stressing the therapeutic principles which seem to be most suitable for management of this insidious complication of splenectomy.

Anemia, Hemolytic

Hemodynamic effects of somatostatin in insulin-dependent diabetic subjects.

The aim of the present study was to evaluate possible hemodynamic effects of somatostatin in insulin-dependent diabetic subjects. For this purpose, 7 insulin-requiring juvenile-onset diabetics were submitted to a short-term infusion of cyclic somatostatin (250 micrograms/h, over 2 h) or saline in randomized order. Somatostatin infusion resulted in a progressive and significant decrease in heart rate, stroke volume, cardiac index and velocity circumferential fiber; on the other hand, left ventricular ejection time was augmented by somatostatin. None of these effects was seen in the saline control study. We conclude that somatostatin exerts a negative inotropic effect in insulin-dependent diabetes.

Adult

[Polygraphic study of systolic rates after intravenous administration of salbutamol].

The effects of salbutamol on the polygraphic pattern were studied in 10 patients with chronic obstructive lung disease. Salbutamol, administered by i.v. injection in a single dose of 100 gamma, caused an increase of heart rate, a decrease of PEP (by decrease in the TCI), a decrease of the Wessler's index and an increase of ejection fraction. These results suggest that salbutamol produces an improvement in cardiac function either by a direct inotropic action or by an afterload decrease.

Adult