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G Rorive

Publications and source records attributed to G Rorive.

152 records · Page 9Linked to original sources

Computer-assisted medical care in a haemodialysis unit.

Most computer applications used in dialysis centres process data in batch mode to allow for periodic evaluation and to create a data-bank for research. A system, used for seven years at the University of Liege, achieves these two basic goals; but in addition, it allows for an improvement in patient care, and for a better practical organization of the unit. For each dialysis session, the computer publishes a summary of the data collected during the previous three weeks. Each month, the computer a summary of patients' progress, in an interactive output. As an extension of the medical application, the system gives organizational support to the unit, for example nursing schedules, involving handling biological data, and as a corollary provides extensive data to support clinical research.

Belgium↗

Prevalence of hepatitis G virus in a haemodialysis unit.

BACKGROUND: Recently, a novel blood-borne virus has been identified and named hepatitis G virus. Transfusion is the main route of transmission. It is known that patients on maintenance dialysis are more susceptible to infections with parenterally-transmitted viruses than the general population. The aim of the present study was to determine the prevalence of hepatitis G infection in a Belgian dialysis unit. METHODS: The entire population of our dialysis unit (82 patients) was tested for the presence of hepatitis G virus (HGV) by reverse transcriptase polymerase chain reaction. History of transfusion or renal transplantation, coinfections with hepatitis B and C viruses, and serum aminotransferase levels were also tested. RESULTS: Thirteen patients (16%) were found positive for HGV-RNA. Among these patients, 69.2% were infected by the G virus alone, 15.4% were coinfected with B virus, and 15.4% with C virus. All but one patient had a history of transfusion. Ten of the thirteen infected patients (77%) had normal aminotransferase (< 30 UI/l). Three patients had elevated aminotransferase levels (23%); one was coinfected with B virus, one with C virus, and the last one had a diabetes-induced fatty liver infiltration. No liver biopsies were performed. CONCLUSIONS: It is concluded that infection with G virus is common among dialyzed patients. This high rate of infection could be related to previous transfusions, but may as well be due to nosocomial transmission. In our series, at least one patient has been contaminated by another road than transplantation or transfusion. Finally, it does not appear clearly that chronic infection with hepatitis G virus induces liver disease, as defined by elevated aminotransferase level.

Adolescent↗

[The medical decision for the non-competent patient].

The evolution of the therapeutic relation from a paternalistic to a collaborative one has increased the legal and ethical problems related to the medical care in non competent patients. The recent Belgian law on the rights of the patient (August 22, 2002 ) and the advice of the Belgian Council of the Medical Association on this matter provide the practitioner with clear directives. However, the responsibility of the final decision always remains in the hands of the medical doctor as the protector of the patient.

Belgium↗

Aortic collagen biosynthesis during renal hypertension, pregnancy and hypertension during pregnancy in the rat.

The synthesis and deposition of collagen and other proteins has been measured in the aorta of the rat by radiolabeling in short term organ culture. Under these conditions, the synthesis of collagen and other proteins is linear for at least five hours. Autoradiography demonstrates a labeling in all cell layers and protein deposition in the extracellular matrix. Hypertension was induced by renal ischemia using Goldblatt's technique. The synthesis and deposition of collagen was stimulated in aorta from the first week of hypertension and in pregnancy, and was even more increased in hypertensive pregnant animals. Reserpine suppresses the rise in blood pressure in operated animals and prevents these modifications.

Animals↗