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Biomedical subjects

G Roper-Hall

Publications and source records attributed to G Roper-Hall.

18 recordsLinked to original sources
PubMed2000

Update on orbital floor fractures: indications and timing for repair.

There has been much discussion and controversy over the management of blowout fractures of the orbit. At various times, recommendations have included operating on all orbital floor fractures and operating on none of them. As our understanding of blowout fractures and their sequelae has evolved over time, so too has understanding of when and whom would benefit from surgery. In the past, the focus has often been on early versus late repair. The focus should really be on understanding the mechanisms of diplopia and enophthalmos in orbital floor fractures, the best way to evaluate a patient, and, finally, the best method of restoring maximal function and appearance. We present herein a historical perspective on the management of orbital floor fractures and our current recommendations for the indications and timing of surgical repair.

Diplopia↗
PubMed1997

Ocular neuromyotonia in Graves dysthyroid orbitopathy.

OBJECTIVES: To describe 2 patients with ocular neuromyotonia in association with Graves orbitopathy and to consider the possible underlying mechanisms. DESIGN: Description of the clinical findings in 2 patients with these conditions. SETTING: Neuro-ophthalmology referral centers. PATIENTS: Two patients, aged 55 and 52 years, had episodic, involuntary periods of vertical diplopia and dysthyroid orbitopathy. INTERVENTION: Treatment with carbamazepine in one patient and external beam radiation therapy in the second patient. MAIN OUTCOME MEASURES: Frequency and duration of episodic spasms of the extraocular muscles. RESULTS: Although radiation therapy is the most common association with ocular neuromyotonia, it cannot explain the involuntary contractions of extraocular muscles in all affected patients. Other mechanisms must be involved, such as those discussed in this article. CONCLUSION: Ocular neuromyotonia is described in 2 patients with dysthyroid orbitopathy, confirming previous findings. Possible mechanisms are given.

Analgesics, Non-Narcotic↗
PubMed1996

Pseudotumor cerebri associated with cyclosporine use.

PURPOSE: An 11-year-old boy had a one-month history of horizontal diplopia. Three years earlier, he had undergone allogeneic bone marrow transplantation complicated by graft versus host disease. METHODS: The patient had esotropia and bilateral optic disk edema. A magnetic resonance imaging scan disclosed no intracranial lesion. The opening pressure of the lumbar puncture was 500 mm of water. Pseudotumor cerebri secondary to cyclosporine was diagnosed. RESULTS: The patient improved with resolution of his esotropia and diplopia within five days of discontinuing his cyclosporine. The optic disk edema resolved within three months. CONCLUSION: Cyclosporine must be added to the list of medications with a known association with pseudotumor cerebri.

Bone Marrow Transplantation↗
PubMed1982

Atypical oculomotor paresis.

A series of patients is presented with partial oculomotor palsies. The accompanying signs of neurologic dysfunction are indicative of a mesencephalic lesion. The peculiar anatomy of the third cranial nerve permits one to infer precise localization of the lesions.

Adolescent↗
PubMed1980

Binocular diplopia associated with subretinal neovascular membranes.

A series of patients were seen with binocular diplopia secondary to subretinal neovascular membrane in one eye. The pathophysiology underlying the diplopia is the establishment of rivalry between central and peripheral fusional mechanisms. This diplopia is not relieved by appropriate prism therapy.

Adult↗
PubMed1977

Experimental internuclear ophthalmoplegia.

A midline experimental lesion separating the medial longitudinal fasciculi at and below the level of the abducens nuclei without damaging either fasciculus at the level of the nuclei has produced defects of ocular motility resembling those of clinical internuclear ophthalmoplegia. Electromyographic recordings during lateral gaze demonstrate: (1) lack of inhibition of the lateral rectus muscle in the adducting eye, (2) delayed inhibition of the medial rectus muscle in the abducting eye, and (3) occasional evidence of excitation of the medial rectus muscle of the abducting eye probably associated with pupillary constriction. The presumed physiologic mechanisms involved in conjugate gaze movements are discussed in the light of the experimental findings.

Animals↗
PubMed1975

Ocular motor dysfunction in total and hemicerebellectomized monkeys.

Studies of ocular motor function in monkeys undergoing either total or hemicerebellectomies has revealed the following abnormalities which can be attributed to cerebellar dysfunction: 1. Loss of smooth pursuit movements 2. Gaze-fixation nystagmus 3. Loss of inhibitory input on the vestibular apparatus reflected in a decreased latency and prolonged response to caloric stimuli. It is intimated that the role of the hemicerebellum deals with ipsilateral tone and its effect on eye movements.

Animals↗