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Biomedical subjects

G Robinson

Publications and source records attributed to G Robinson.

At least 163 records · Page 9Linked to original sources

Age and oxygen toxicity related fluorescence in the honey bee thorax.

The blue fluorescent material in thoraxes of honey bees of known adult age from eclosion to 28 days was measured. The amount was greater in older insects and exposure to ozone (ppm) augmented the rate of accumulation. The nearly constant daylight flying by the bees and the ozone effect suggest radical peroxidative origin of the fluorescence. The material was partially purified by chromatography. It is a relatively non-polar lipid.

Aging↗

Surgical treatment of Wolff-Parkinson-White syndrome: division of an anomalous pathway using the superior approach.

The superior approach to the mitral valve through the dome of the left atrium was used for division of a left free wall anomalous pathway. It has been the approach of choice for mitral valve operations at our institution for the past 15 years, facilitating operations particularly when the left atrium is normal in size. Other approaches to the mitral valve are discussed.

Adolescent↗

Location and release of TRH and 5-HT from amphibian skin.

The occurrence and release of thyrotrophin-releasing hormone (TRH) and 5-hydroxytryptamine (5-HT) from amphibian skin have been described by previous investigators. In the present study, the precise location and site of release of TRH and 5-HT from the skin of Rana pipiens and Xenopus laevis have been examined using a combination of procedures including immunohistochemistry, HPLC, and radioimmunoassay. The results indicate that TRH is located specifically within the dermal glands of these species, and that both TRH and 5-HT are discharged from these glands following adrenergic stimulation. The origin and functional significance of these substances in amphibian skin granular glands are discussed.

Animals↗

Internal mammary artery-saphenous vein composite conduit: an alternative for the proximal coronary anastomosis.

A patient who had previously undergone saphenous vein bypass grafting was seen with recurrent angina requiring reoperation. At the second operation, technical problems with the ascending aorta ultimately excluded its use for the proximal anastomosis for the second of two bypass grafts. Anastomosis of the left internal mammary artery to the proximal end of the saphenous vein graft successfully resolved the problem.

Angina Pectoris↗

Naturally arising tumors of the inbred WAB/Not rat strain. I. Classification, age and sex distribution, and transplantation behavior.

During a 3-year period, 97 naturally arising tumors were collected from an inbred colony of WAB/Not rats. These tumors were largely confined to the breeding groups of approximately 5,300 female and 2,700 male rats retained up to 2 years of age. The tumors included 39 nephroblastomas and 41 mammary tumors (24 of which were histologically benign); the remaining tumors were mainly connective tissue sarcomas and skin tumors with 1 lymphoma and 2 gastrointestinal lesions. With the exception of the incidence of mammary tumors, males and females had similar tumor incidence, although nephroblastomas in female rats had a marked preference for growth in the left kidney. Most tumors occurred in the first year of life, especially the histologically malignant mammary tumors and the nephroblastomas. Of the tumors investigated, 31 were transplantable. Poor correlation between histologic malignancy and transplantation was seen with the mammary tumors. Only 50% of the nephroblastomas were transplantable. Although most transplanted tumors retained histologic characteristics of the primary tumor, 1 mammary tumor, 1 gastrointestinal tumor, and 1 nephroblastoma deviated from this general finding. In the case of this nephroblastoma, separate transplant lines from opposite poles of the primary tumor also showed differences in histology.

Age Factors↗

A formalin fixative for immunochemical and ultrastructural studies on gastrointestinal endocrine cells.

Using indirect immunofluorescence, indirect immunoperoxidase, and unlabelled antibody enzyme techniques, gastrin, pancreatic glucagon, insulin, and somatostatin were localised in sections of both wax- and resin-embedded tissues that had been fixed in a buffered formalin solution. Ultrastructural preservation of the resin-embedded samples was also adequate for combined electron microscopy and light microscope immunochemistry. As the fixative concerned is stable it can be permanently available in surgical units. It is suggested, therefore, that this fixative should prove useful as an alternative to buffered formaldehyde, which must be freshly prepared from paraformaldehyde powder, in institutions where specimen collection is difficult or which have to refer cases with an endocrine involvement to other laboratories for immunochemical and fine structural examination.

Digestive System↗

Olfactory mucosa in herpes simplex encephalitis.

The olfactory mucosa was examined in three patients dying from herpes simplex encephalitis. It showed changes attributed to infection by the herpes simplex virus. It is suggested that in some patients encephalitis may be a complication of infection of the olfactory mucosa.

Adult↗