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Biomedical subjects

G Rizzo

Publications and source records attributed to G Rizzo.

313 records · Page 18Linked to original sources

[Researches on antibiotic-resistance in "Shigella sonnei" and "flexneri" and in "Salmonella typhimurium" (author's transl)].

Ampicillin (A), streptomycin (S), aminosidin (K), chloramphenical (C) and tetracycline (T) resistance was investigated in 130 S. typhi murium, 18 Shigella flexneri and 13 Shigella sonnei strains, recovered from enteritis cases in 1970-1973. All Salmonella and 70% Shigella strains (without any appreciable differences between Sh. sonnei and flexneri) were found resistant and most multiresistant. A-S-K-C-T resistance was frequently found: in 48% of the Salmonella and 12% of the Shigella strains. As for resistance transfer by conjugation, it was obtained in more than 90% of the resistant strains. The Authors, after some remarks about transferable resistance factors diffusion, give some advices on antibiogram making technique.

Anti-Bacterial Agents↗

[Researches on metal-resistance and conjugation-transfer in "Escherichia coli" strains (author's transl)].

The resistance for HgCl2, NaAsO2, Co(NO3)2, NiSO4, ZnSO4, Agtno3, and CdSO4 in 40 strains of Escherichia coli, was investigated. In 16 of 23 Hg-resistant strains, resistance transfer was obtained by means of conjugation with Salmonella typhi. Hg-resistance was present only in antibiotic-resistant strains, but no correlation was possible with any antibiotic-resistance determinants: because Hg-resistance transfer may occur independently, and it is possible to obtain clones spontaneously segregant for the mentioned trait. As for the possible mechanisms of bacterial metal-resistance, several hypothesis were prospected, the most credible one that of a detoxification of the metallic salt.

Arsenates↗

[Haemolysin production in "Escherichia coli" strains isolated from urinary tract infection, infantile enteritis and commensal flora (author's transl)].

A total of 933 strains of Escherichia coli, of which 146 isolated from cystitis cases, 515 from infantile enteritis one and 272 from healthy individuals, have been chicked for haemolytic activity. A good 45.2% of the strains from the urinary tract, but only 7.7% of the enteritogenic and 3.6% of enteric commensal ones were found to be haemolytic. Among the cystitis strains, a high number (30/146 with an incidence of 20.5%) belonged to O6 serogroup. Serotype O4 was also frequently found (9.5%). Among the urinary strains, of which more than half (53.4%) were included in O1 up to O10 serogroups, the haemolytic ones were comprised in O2, O4, O6, O55 and O75 serogroups. Finally, the Authors point out the importance that the haemolytic activity of Escherichia coli may have in the pathogenesis of the renal injury at the light of some late experimental works.

Cystitis↗

[Studies on the frequency of Corynebacterium diphtheriae carriers among students of the elementary schools in Bari].

The morbidity of diphtheria reported in Bari in 1970 and in 1971 was 17.1 and 19.1 for 100000 inhabitants; in the same years the national average was respectively 1.6 and 1.3. In a epidemiological research carried out in the same period in 1017 school-children of Bari not previously selected, 45 carriers of C. diphtheriae (4.42%) were identified. Toxigen strains were isolated from 11 carriers (1.08%). The frequency of carriers was higher in the school-children 9-11 years aged (6-04%), lower in the school-children 6-8 years aged (2.99%).

Age Factors↗

[Morgagni-Larrey hernia. A case report].

The authors report a case of Morgagni-Larrey hernia. It is anuncommon diaphragmatic hernia, often asymtomatic and occasionally found. The authors point out the disease's clinical, diagnostic and therapeutic aspects. The hernia's repair can be done both abdominal and thoracic via. The operation is always advisable as well as in asymptomatic pazients.

Follow-Up Studies↗

Denervation muscular atrophy. Studies on the soleus muscle of the albino rat (LM, TEM, immunofluorescence, image analysis).

In previous researches the Authors hypothesized that the loss of cytoskeletal proteins such as desmin and vinculin lead to degenerative ultrastructural changes which occur in muscular disuse atrophy. In order to support this hypothesis they carried out a morphometric, structural, ultrastructural and immunofluorescence study on the soleus muscle of albino rats after resection of the ischiatic nerve. It was demonstrated that a chronological sequence of the damage took place in particular three levels of damage. The last level of damage proved to be irreversible; the first level assured complete recovery in the case of rapid reinnervation, whereas the possible reversibility of the second level remained open to question. The disappearance of vinculin and desmin was observed in a period between 72 hours and 7 days, i.e. before the appearance of ultrastructural damage. On this ground the Authors explained the correlation between the loss of the proteins and degenerative changes. In conclusion the Authors correlated the gene expression of cytoskeletal and contractile proteins with the neuropeptides released by motor axon.

Animals↗