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Biomedical subjects

G Rizk

Publications and source records attributed to G Rizk.

At least 19 recordsLinked to original sources
PubMed1997

Hypocalcemia and skeletal disease as presenting features of celiac disease.

OBJECTIVE: To describe 15 patients examined for hypocalcemia, skeletal disease, or both in whom the diagnosis of celiac disease was subsequently made. DESIGN: Observational case series. PATIENTS: Fifteen patients (7 women and 8 men) were examined for hypocalcemia (n = 11), skeletal disease (n = 3), or both (n = 1). The diagnosis of celiac disease was subsequently made. The mean age of the patients was 62 years, and 11 patients were 60 years of age or older. RESULTS: Four patients had no gastrointestinal symptoms, 7 patients had mild or intermittent gastrointestinal symptoms, and 4 patients had persistent diarrhea. Ten patients had experienced weight loss. The serum total alkaline phosphatase level was elevated in 10 of 15 patients, the parathyroid hormone level was elevated in all patients, and the urinary calcium level was low in all 6 of the patients tested. The level of 25-hydroxyvitamin D was frankly low in 4 patients, marginal in 8 patients, and normal in 3 patients. Bone mineral density was reduced in all 8 patients in whom it was measured. CONCLUSIONS: Celiac disease should be considered in patients with unexplained metabolic bone disease or hypocalcemia, especially because gastrointestinal symptoms may be absent or mild. Advanced age does not exclude the diagnosis of celiac disease.

Adult↗
PubMed1990

Ethanol-induced esophageal motor disorder: development of an animal model.

Abnormal esophageal motility has been reported in alcoholics. This includes abnormally high esophageal contraction amplitudes (ECA) and elevated lower esophageal sphincter pressures (LESP). However, an animal model is lacking for evaluating the underlying mechanisms. To develop such a model of ethanol-induced esophageal motor dysfunction, esophageal manometry was done in control, chronically intoxicated, and withdrawing cats. Ethanol was administered for at least 30 days via gastrostomy tube and blood alcohol levels, typically 300 mg/dl, were adjusted to maintain inebriation. LESP and upper (striated muscle) and lower (smooth muscle) ECA were elevated in male withdrawing cats. In intoxicated cats only upper ECA was elevated. Surprisingly, LESP and ECA were not significantly affected in females. Duration of ECA was prolonged in both male and female intoxicated cats. These findings indicate that: (1) similar to withdrawing men, ECA and LESP are elevated in withdrawing male cats; (2) ethanol-treated cats are an appropriate model for studying the mechanism of ethanol effects on esophageal motor function; (3) gender has a significant role in influencing the effects of alcohol.

Animals↗
PubMed1985

The role of breast scintigraphy in detecting breast masses.

127 breast scans were performed on 83 female patients using technetium-99m diphosphonate. 46 out of 48 patients with breast cancer had positive breast scans manifested by a focal increased uptake in 37 patients and a diffuse increased uptake in the remaining 9 patients. Benign breast lesions such as fibrocystic disease, fibroadenoma and fat necrosis may also concentrate the radioactive agent in a focal or a diffuse pattern. So breast scanning is a sensitive though nonspecific modality to detect malignant breast lesions and it is worthwhile performing it on all women referred for bone scan.

Breast↗
PubMed1980

Angiographic aspects of traumatic intracranial aneurysms following war injuries.

Intracranial aneurysms following head injuries occur very rarely. Only 15 cases following injuries by missiles or shrapnel have been reported in the world literature. The angiographic findings in seven cases injured during the recent fighting in Lebanon, are described. The relatively high frequency of occurrence of these aneurysms in our cases might be explained by the fact that they were injured by low velocity missiles. A high velocity missile would disrupt an artery completely. It is also of interest that most of the aneurysms originated from arterial branches along the path of the foreign body, but not in contact with it. Unlike congenital aneurysms, they bore no relationship to arterial bifurcations and, unlike aneurysms following closed-head injuries, none involved the large basal arteries. None of them had a neck, and a mass effect due to bleeding was found in six of the cases.

Cerebral Angiography↗
PubMed1975

Cavernous hemangioma of the heart: case report and review of the literature.

A case of diffuse cavernous hemangioma of the heart discovered incidentally during life is reported. Resection of the tumor was impossible at operation. Two similar cases were found in the literature. Radation therapy is suggested, and the importance of a simple blood pool scan in the investigation of paracardiac masses is stressed.

Female↗