[Forces in driving in tibial intramedullary nails. II. Impulse loss, energy balance, static and gliding friction].
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Biomedical subjects
Publications and source records attributed to G Ritter.
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Prodromal symptoms and cardiac history were examined in 227 patients with coronary artery disease who were successfully resuscitated after out-of-hospital cardiac arrest. Cardiac arrest was sudden--with either no symptoms or symptoms for less than 1 hour--in 71% of the patients. Nonsudden death--death occurring after more than 1 hour of symptoms--occurred in 29% of the patients. A history of cardiovascular disease was present in 85% of patients with sudden cardiac arrest and in 83% with nonsudden arrest. Cardiac arrest occurred without symptoms in 38% of the patients with sudden cardiac arrest and was the first expression of coronary artery disease in 4% of the entire study group. This study indicates that cardiac arrest usually occurs with symptoms and almost always in the setting of a history of cardiovascular disease.
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The signs and symptoms of severe Guillain-Barré-Strohl syndrome are dominated by extensive motor and sensory disorders of the peripheral nervous system. Paralysis of the respiratory muscles is common. Frequently the autonomic system is involved as well, with numerous, often life-threatening, regulatory disorders. Of 68 patients with the disease observed within a span of 5 1/2 years, 21 with such severe forms required intensive care.
We report on two patients who suffered from bullous pemphigoid and developed cerebral infarctions during the course of this autoimmune dermatosis. The first patient who had a bullous dermatosis for three weeks presented with a sudden paresis of her right arm. She improved under steroid therapy and developed a left sided hemiparesis after steroids were reduced for diagnostic purposes. The second patient developed signs of brain stem infarction during the course of full-blown bullous pemphigoid. Neither patient had known risk factors, signs of atherosclerosis or cardiac embolism. Both patients improved with steroids and azathioprine.
Previous investigations (cross-sectional and time series studies) to conditional structures of heterostereotypes toward epileptics are mainly based on the interview schedule of Caveness (1949). This item pool seems insufficient to parametrisize the horizon of attitudes toward epileptic persons. Antonak and Rankin (1981, 1982) found a higher degree of dimensionality of stereotypes by application of their ATPE scale (Attitudes toward persons with epilepsy). Therefore, studying the complex interaction of attitudes and knowledge about epileptics, we presented an adapted and translated German version of the ATPE to a sample of 372 volunteers. The dimensional decomposition of the 32 items resulted in five factors: 1. attitudes regarding education and social integration (EDUCINT), 2. attitudes regarding working behaviour (WORK), 3. negative attitudes regarding reproductive behaviour (REPR), 4. open discrimination (DISC), 5. passive tolerance (PASTOL). Variance analytical investigations showed a complex pattern of stereotypes in the sample in relation to sociodemographic background parameters.
Under normal conditions the portion of any antigen specific IgG of total IgG is identical in serum and CSF. This thesis was investigated in 51 patients who were found to have seropositive syphilis without CNS involvement. For this purpose a special index (ITpA-index) was used, based on the ratio of specific IgG per total IgG of CSF to specific IgG per total IgG of serum. This index has a value of 1 (0.5-2), if there is no antibody synthesis in the CNS, as confirmed on the 51 seropositive control patients. In patients with syphilitic CNS involvement the index rose above 2 (3-430), due to local antibody synthesis in the CNS. When there is an ITpA-index below 2.0 in patients with seropositive syphilis who show any CNS symptoms whatsoever, it can be presumed that the actual CNS disease is not a consequence of the former syphilitic infection, but is caused by a condition other than syphilis. In 6 patients with reactive syphilis tests, moderate CSF pleocytosis and increased CSF total IgG, the ITpA-index was below 0.5. Among these 6 patients the inflammatory CNS process was non-syphilitic. The principle of the ITpA-index is applicable to other bacterial or viral CNS diseases insofar as a local humoral immune response takes place. This could be demonstrated in cases of herpes zoster.
The analysis was elaborated in an epidemiological area. 92 patients with multiple sclerosis were researched and interviewed under biographical and psychosocial aspects. The most limiting factor in the organic view was the motoric deficit-provoking negative social coping of the disease. The family members usually supported their patient in coming out with the different handicaps; but psychosocial disturbances often were to be seen. Only one third of the patients held their job or were managing the household. One half of the sample suffered on pathological coping with the disease, showed signs of isolation and resignation. A quarter of them lived in psychosocial extrem conditions. A sufficient income had nearly half of the patients. The medical care was optimal in all cases. For women a help in the household often failed. The study enlighted the necessity of a therapeutic program involving a normalisation of the disease.
The effect of bystander cardiopulmonary resuscitation (CPR) was studied in 2142 emergency medical service (EMS) cardiac arrest runs. When bystander CPR was administered to cardiac arrest victims, 22.9% of the victims survived until they were admitted to the hospital and 11.9% were discharged alive. In comparison, the statistics for cardiac arrest victims who did not receive bystander CPR were 14.6% and 4.7%, respectively (p less than 0.001). A critical factor in patient survival was the amount of time that elapsed before the EMS personnel arrived and administered CPR. Patients who received bystander CPR were more likely to have ventricular fibrillation when the EMS arrived. Other factors relating to patient survival were the location of the victim at the time of the cardiac arrest and the age of the victim. Understanding these factors is important in developing community strategies to treat patients with cardiac arrest out of hospital.
Resuscitated victims of cardiac arrest with coronary heart disease represent a group of patients with an accelerated mortality rate. Among 227 such patients in our follow-up study, 20% had died at 1 year and 50% were dead in slightly over 3 years. Predictors of death were related to use of digitalis, elevated blood urea nitrogen, cerebral vascular accident, previous myocardial infarction, and age. In a subset of 103 patients in whom ambulatory electrocardiographic recordings were available within 3 months of the arrest event, the presence of complexity and high-frequency ventricular premature beats (VPBs) (greater than or equal to 25/hr) were added to the mortality predictors of digitalis and diuretic therapy and elevated blood urea nitrogen. An almost equal number of patients died suddenly and nonsuddenly. Predictors of sudden death were treatment with quinidine and paired VPBs. Occurrence of arrhythmias was an important addition to the previous mortality predictors related to left ventricular dysfunction.
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The potential of some Lactobacillus, Staphylococcus and Streptococcus strains for producing putrescine and cadavering during growth in vacuum packed beef was studied. Throughout the six weeks storage at 4 degrees C the samples were sensorily assessed at regular intervals, and their pH values and diamine contents were determined. The amines were quantified by means of capillary gas chromatography. The putrescine and cadaverine contents remained within the range of the initial values until overt spoilage at the end of the sixth week (at about 0.08 mg amine/100 g).
The classification of the proximal humeral fractures according to the four-segment concept of Neer has proven to be very useful. It not only considers the fracture itself but also lesions of the soft tissue. Adapting Neer's concept we propose a modified classification of the proximal humeral fractures which we believe is clearer and more practicable. This classification is illustrated by means of drawings and typical roentgenograms. The description of the different fracture-types includes the mean characteristics such as fragment-displacement, status of the rotator cuff and blood circulation to the head segment.
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Posterior subacromial dislocations of the shoulder are usually accompanied by compression fractures of the antero-medial part of the humeral head; the lesions have a wide variability. Four case reports are presented and the problems of radiologic analysis are discussed.
Circulatory and respiratory reactions during the implantation of joint endoprostheses have been observed for years. The components of the bone cements used for anchoring (methyl methacrylate monomer) or the outpour of bone marrow substances from the affected bone marrow cavity are thought to be chiefly responsible for these effects. However, our previous investigations demonstrated unambiguously that reactions of this type can be attributed to direct nervous-reflex mechanisms triggered by the pressure rise in the medullary canal, and that, in addition, bone marrow embolism plays a part in serious circulatory incidents. The investigations on which the present paper is based have confirmed the mechanism of circulatory reactions triggered by direct nervous reflex and have shown once again that the release of cement monomers is not of any significance, at least not in animal experiments. In regard of the characteristics of these reflex processes, it has been possible to show by both surgical and pharmacologic interventions in the vegetative nervous system, performed before and during pressure experiments, that these reflex processes are caused not so much by an increase of the vagus tone as by a central inhibition of the sympathicus. Neither administrations of atropine nor bilateral cervical vagotomy are able to prevent the reactions. This was only possible under the influence of a ganglion blocker.
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A two year old boy was seen in the orthopedic clinics because of typical symptoms of Legg-Perthes disease, a scintigraphy with Technetium99m showed a distinct deficiency of nuclear activity in the femoral head which is characteristic of the early stage of Legg-Perthes disease. A routine blood count lead to the diagnosis of acute lymphoblastic leukemia. The boy was treated according to the Austrian cooperative leukemia protocol and complete remission was achieved. No orthopedic treatment of the femur head necrosis was done, after eight weeks of treatment with multiagent chemotherapy the boy started to walk again and subsequently became free of all symptoms of Legg-Perthes disease. A scintigraphy done eight weeks after the initial scintigraphy showed that the deficiency of radionuclear activity of the femoral head was nearly vanished. This case illustrates the variability of bone involvement in acute lymphoblastic leukemia, which often is the most prominent symptom at an early stage of the disease.