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Biomedical subjects

G Rifle

Publications and source records attributed to G Rifle.

At least 73 records · Page 4Linked to original sources
PubMed1987

[Program of continuous ambulatory peritoneal dialysis and renal transplantation in insulin-dependent diabetics in the terminal stage of renal insufficiency].

A program of continuous ambulatory peritoneal dialysis (CAPD)-renal transplantation was set up on less than 55 years old insulin dependent diabetics with end stage renal failure. Ten patients were included (age range: 9-45 years, mean: 35.6). All these patients had many complications: retinopathy, arteritis, ischemic heart disease, hypertension, neuropathy, cutaneous infection. One patient refused CAPD and was hemodialyzed for 8 months before grafting. Nine patients were treated for 3 to 45 months (mean: 14.8). During CAPD therapy, better control of hypertension and blood glucose levels were achieved. Five patients received a cadaver renal transplant 3 to 27 months (mean: 13.3) after starting CAPD. All these transplants are functioning 12 to 62 months after grafting (mean: 26.4). No post-operative complications can be directly related to CAPD. No vascular complications occurred during post-transplant follow-up. So, an integrated program CAPD-renal transplantation could be of value for young insulin-dependent diabetics.

Adult↗
PubMed1986

[Acute granulomatous interstitial nephritis and hepatitis caused by drugs. Possible role of an allopurinol-furosemide combination].

Acute granulomatous interstitial nephritis and acute granulomatous hepatitis were simultaneously observed in the same patient. Clinical and anamnestic arguments suggest that allopurinol could be responsible for this double localization, but a possible part played by furosemide cannot be excluded. The patient spontaneously recovered without corticosteroid therapy. Such an acute drug induced association did not have been proved so far.

Acute Disease↗
PubMed1984

Successful plasma exchange in type 1 leprosy reversal reaction.

A 24 year old man admitted to hospital with borderline lepromatous leprosy was treated with rifampicin, dapsone, and clofazimine. After four months he developed a reversal reaction and the diagnosis was modified to borderline tuberculoid leprosy. The dose of clofazimine was raised and prednisolone added to the regimen without any symptomatic response. His condition improved dramatically after five plasma exchanges on five successive days.

Adult↗
PubMed1983

[Antifactor VIII antibody in Rosai-Dorfman disease].

The case of a 72 year-old man with a sinus histiocytosis is reported. The clinical course was characterised by an hemorrhagic disorder linked to a factor VIII inhibitor. The characteristics of the antibody titer, affinity and saturability have been studied. In an attempt to stop the bleeding treatment included human and porcine factor VIII concentrates, plasmapheresis and immunosuppressive drugs. Repeated plasma exchanges did not modify the inhibitor titer for more than 24 h.

Aged↗
PubMed1982

[Cholesterol embolisms. The anatomical, clinical and pathogenetic aspects. Two case reports, including one case of pseudo periarteritis nodosa (author's transl)].

The authors report on two cases of cholesterol embolism, with one masquerading as polyarteritis nodosa. Cholesterol embolism is a frequent but often unrecognized complication of ulcerous athero-sclerosis. Atherosclerotic foci release a large quantity of cholesterol crystals, spontaneously or after endovascular manipulations, inducing the obstruction of small arteries, 150 to 200 microns in diameter, in various organ or tissues of the organism, such as the kidneys, the spleen, the pancreas, the digestive tract, the skin and the retina. Cutaneous, muscular, reno-vascular and visceral forms have been described, based on the distribution of the crystals. This disease, with its multiple systemic localisations and biological abnormalities may sometimes be confused with polyarteritis nodosa and constitutes the pseudo-PAN form of cholesterol embolism. In all these cases, the simplest method of diagnosis consists in the examination of the fundus and in the analysis of skin and muscle biopsies. Finally, the features of the arteriolar lesions and the lack of immunological disturbances suggest that cholesterol embolisms are form of microcrystalline arteriopathy.

Arteriosclerosis↗
PubMed1982

[Intracranial aneurysm and polycystic kidneys].

Five cases of intracranial aneurysms with polycystic kidneys are reported: --15% of polycystic kidneys have an intracranial aneurysm, and about 4% - 5% of intracranial aneurysms are joined with polycystic kidneys; --the surgical treatment of intracranial aneurysm with this association doesn't present more risk than an intracranial aneurysm, and the surgical prognosis isn't bad; --the pathogeny isn't clear. This association is perhaps a congenital elastic system disease.

Adult↗
PubMed1981

Treatment of idiopathic acute crescentic glomerulonephritis by immunodepression and plasma-exchanges. A prospective randomised study.

A prospective randomised trial was carried out in 14 patients with severe 'idiopathic' acute crescentic glomerulonephritis. The mean percentage of crescents was 78 per cent and 11 patients were anuric at presentation. Eight patients received pulses of methylprednisolone, immunosuppressive drugs and anticoagulants and six the same therapeutic regimen plus plasma exchanges for one to two months. Mean follow-up was 22 months. Recovery was statistically better in the PE+ group (p less than 0.02), but for discontinuation of dialysis, the difference is significant only at two months (p less than 0.02), perhaps because of the small number of patients. For this reason and because all pathological subgroups cannot be analysed separately, this study is continuing.

Acute Disease↗