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Biomedical subjects

G Richardson

Publications and source records attributed to G Richardson.

135 records · Page 8Linked to original sources

Prenatal marijuana use and neonatal outcome.

In a longitudinal study of marijuana and other substance use during pregnancy, women were interviewed at each trimester of pregnancy. Growth parameters, morphological abnormalities and gestational age were assessed for the 519 liveborn singletons. There were few significant effects of marijuana use during pregnancy on birth weight, head or chest circumference, gestational age, or growth retardation after adjustment for covariates using a regression model for analysis. There was a small but significant negative effect of marijuana use during the first two months of pregnancy on birth length and a positive effect of marijuana use during the third trimester on birth weight.

Adult↗

The effects of prenatal tobacco and marijuana use on offspring growth from birth through 3 years of age.

This is a prospective study of prenatal substance use. Women were interviewed during their fourth and seventh months of pregnancy, at delivery, and at 8, 18, and 36 months postpartum. At birth, there were 763 liveborn, singleton offspring in the sample. At each phase, the offspring were examined and measured for growth. Data are presented on the relationship between tobacco and marijuana use and the size of the offspring at birth, 8, 18, and 36 months of age. At birth, there was a significant inverse relationship between tobacco use and weight, length, and head circumference. At 8 months of age, only length continued to be associated with prenatal tobacco exposure. By 18 months of age, there was no relationship between prenatal tobacco exposure and size of the offspring. Prenatal marijuana exposure was only associated with decreased length at birth. Neither tobacco nor marijuana use predicted gestational age or morphological abnormalities.

Child, Preschool↗

Preceptorship and PREPP.

The transition from student to qualified practitioner is a difficult time for nurses. In order to facilitate a less traumatic change in role and status, the UKCC has advocated a period of support under the guidance of preceptors.

Education, Nursing, Continuing↗

Levamisole: a double blind immunological study.

The immunological effects of a 4-week course of levamisole have been assessed by a randomised double blind study of a group of cancer patients judged to have a poor prognosis. No change in immunological status was recorded during a 6 months follow up, using a battery of tests including DNCB response. Mantoux response, lymphocyte count, PHA stimulation and serum immunoglobulin levels. 38% of patients complained of side-effects from the levamisole and 17% stopped the treatment. It is concluded that any beneficial effects of levamisole in patients with advanced cancer may be mediated by a non-immunological mechanism, or by some immunological process other than those studied here, or may require a longer period of administration than 4 weeks. Variation in skin test results in the placebo group throw some doubt on previous reports of immunopotentiation of cancer patients by levamisole.

Adjuvants, Immunologic↗