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Biomedical subjects

G Rey

Publications and source records attributed to G Rey.

At least 37 records · Page 2Linked to original sources
PubMed1978

[Diagnostic value of radionuclide bone imaging in monitoring skeletal metastases (author's transl)].

In typical cases with pelvic metastases a close relationship is demonstrated between nuclear medicine and radiologic findings depending on the kind of therapy. For this reason total body radionuclide studies should not only be recommended for screening but also for therapeutic monitoring. Positive radionuclide findings should be supplemented by roentgenologic studies of the areas selected in that way.

Adult↗
PubMed1978

[Management of bone metastases. Indication for radiotherapy and surgical internal fixation (author's transl)].

Radiotherapy of bone metastases can achieve in up to 78% of patients complete relief of pain. Recalcification avoids pathological fractures and beginning compression of the spinal cord. Depending on size and site of the osteolytic process a prophylactic surgical stabilisation will be necessary. Bone metastases are a sign of generalized disease. Systemic therapy should be provided in addition to local therapy.

Adult↗
PubMed1978

[The problem of malignant degeneration in case of multiple neurofibromatosis (author's transl)].

Within less than one year, our hospital received three cases of malignant manifestation in case of multiple neurofibromatosis. If the histological findings and the neurogenic origin of the malignant tumor are evaluated very critically, the malignant suppression of the differentiation of one or more neurofibromas in case of multiple neurofibromatosis must be considered as occuring very rarely. If in case of a neurofibromatosis a malignant manifestation is found, it has to be examined very carefully by tissue specimens of numerous spots (Loehr and Willebrand), furthermore the neurogenic origin must be ensured (Zuelch). There are three clinical possibilities: 1. Sarcomatous degeneration of a neurofibroma with demonstrable neurogenic origin. 2. Histological appearence of a malignant suppression of the differntiation of a neurofibroma with benign clinical course. 3. Independent sarcoma as second disease without original connection to an existing multiple neurofibromatosis.--A critical evaluation of our cases showed that there was only one case of malignant tumor with neurogenic origin, namely a neurofibrosarcoma originating from a multiple neurofibromatosis.

Adult↗
PubMed1977

[Phospholipase of rat intestine: mode of action].

Phospholipase activities of rat intestinal mucosa homogenate have been determined from lysophosphatidylcholines [14C] and phosphatidylcholines [-3H-14C]. In the presence of phosphatidylcholines, at pH 6.5, the homogenate has a phospholipase B activity. At pH 8.5, a phospholipase A2 activity was shown. In the presence of lysophospatidylcholines, at pH 6.5, we notice a lysophospholipase A1 activity. A kinetic study of the reactions allows us to separate the activity B into a phospholipase A2 activity and a lysophospholipase A1 activity. Thus, it appears that the total phospholipase activity of rat intestinal mucosa would results from a phospholipase A2 activity and a lysophospholipase A1 activity.

Animals↗
PubMed1977

[The influence of quality of irradiation on survival in inoperable bronchial carcinoma (author's transl)].

Irradiation of inoperable bronchial carcinoma with constant ortho-volt technique has worse results than with mobile irradiation, since the individual dosage in several fields can be raised without damaging the skin. With mega-voltage limits of skin tolerance, changed absorption or protection of healthy tissues are absent, so that it is easier to deliver doses affective on the tumor. Survival-rates can be related to dosage. During the first few years similar doses of mega-voltage lead to more frequent survival. In part such results depend on differences in standard dosage with the various techniques. More important for the worse results of orthovoltage treatment are the higher doses, the greater volume of irradiation and scatter which may cause greater damage to immunity. 5 years survival of patients with a central inoperable bronchial carcinoma is hardly altered but during the first 2-3 years megavolt therapy is clearly more effective.

Carcinoma, Bronchogenic↗
PubMed1977

[Contribution to the radiation therapy of cerebral tumors (author's transl)].

Postoperative radiation therapy chiefly has to be regarded under the aspects of prevention or delay of recurrences. Primary radiation therapy without surgical extirpation of the principal mass of the tumor generally represents a palliative measure. As the radiosensitivity of a cerebral tumor is not exclusively dependent on the histological picture, histology should not influence the indication for radiotherapy. A diagnosis however, based on all clinical means, being reliable to a high degree, is a condition of the radiation therapy of brain tumors without a clear histologic determination. In this paper are reported the results of treatment from 132 intracranial tumors, and compared with data from literature.

Adenoma↗
PubMed1976

[Results of radiotherapy of bronchial carcinoma (author's transl)].

In a joint retrospective study by 17 radiotherapy clinics in German-speaking countries the results of treatment of bronchial carcinoma after radiotherapy were analysed in 7503 cases. The age peak was between the 60th and 70th year. Squamous-cell carcinoma was the most frequent histological type, followed by anaplastic carcinoma, with adenocarcinoma being rare. There was a high proportion of histologically not clearly identified cases (27% in central and 35% in peripheral carcinomas). Survival rate at one year was 31% for central (3662 patients) and peripheral (961 patients) tumours, but only 2% at five years. Prognostically there was no difference between histological types and kind of radiotherapy or technique, but total dose affected survival rate. At a total dose of less than 5000 rd the survival rate at five years was minimal. The prognosis of combined surgical and radiotherapeutic measures was slightly better than with a radiotherapy alone, but results were unpredictable for the individual case. It is concluded that radiotherapy aiming at cure should be used in imoperable bronchial carcinoma if the tumour state and general condition of the patient appear to make a cure possible. But if this is not the case, radiotherapy should be used only palliatively, i.e. only to ameliorate symptoms.

Adenocarcinoma↗
PubMed1976

[Leiomyosarcoma of the left side of the heart with a mitral symptomatology. Echocardiographic study].

A patient presented with the clinical findings of mitral stenosis, and angiocardiography revealed an intracardiac tumour. It was found at surgery to be a leiomyosarcoma, occupying almost the whole of the left auricle, and infiltrating the inter-atrial septum, the atrio-ventricular ring at the posterior commissure, and the posterior surface of the left ventricle. A mass with three lobes and a pedicle attaching it to the posterior wall and the ring of the mitral valve was found within the cavity of the left ventricle. The findings on echocardiography corresponded with the anatomical findings; but after surgery, ultrasonic investigation was found to be unreliable at detecting the unresected portion of the tumour, which was situated in the right postero-inferior region of the auricle of the left atrium.

Echocardiography↗
PubMed1975

[Variations in kidney location and consequences for the radiotherapy of kidney neoplasms in the optimization of irradiation planning].

Related to the discussion of optimal radiotherapy planning for the treatment of intrathoracal and intraabdominal tumors being located near the diaphragm, the question arises all over again, if the tumor or the former tumor-bed really are completely encompassed by treatment fields if the patient's topography has changed during a series of irradiations. Using a therapy simulator, the variations of the situs of kidneys are investigated in 20 patients. Changes of the location, which ought to be considered for radiotherapy treatment planning, are observed while changing from dorsal to abdominal position or due to exspiration and inspiration. Hence, consequences result concerning the precision of irradiation planning especially with regard to the sound kidney to be spared. Altogether, a better adjustment to individual features of the topographical correlations is realized. The accurate encompassment of the target volume and the careful sparing of the sound kidney resulting therefrom are justifying that much time must be spent on irradiation planning.

Cobalt Radioisotopes↗
PubMed1975

[Results of ortho- and megavolt therapy of inoperable bronchial carcinoma].

Survival rates of patients with inoperable, histologically verified bronchial carcinoma are compared as to orthovoltage or megavoltage radiation therapy. With megavoltage therapy, better survival rates are obtained after one or two years; later on, an approximation of the comparison groups is to be observed with regard to life expectancy. The improvement in one-year and two-year survival rates does justify the application of megavoltage therapy.

Adult↗