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Biomedical subjects

G Re

Publications and source records attributed to G Re.

At least 91 records · Page 5Linked to original sources

Histometric analysis of white pulp arterial vessels in congestive splenomegaly.

A quantitative study of white pulp arterial vessels has been carried out in congestive splenomegaly with hypersplenism. Arteries and arterioles with periarterial lymphatic sheath (PALS) in abnormal spleens show an absolute volume and total length higher than in controls. Moreover, they present a luminal diameter significantly lower than normal. These findings demonstrate an increase of the white pulp arterial bed in congestive splenomegaly. Thus, the arteries with PALS participate in the complex vascular rearrangement which supports the blood hyperflow in congestive splenomegaly.

Hepatitis, Chronic↗

Red pulp arterial terminals in congestive splenomegaly. A morphometric study.

A quantitative analysis of the red pulp arterial terminals (comprising arterioles = penicilli, arterial capillaries and sheathed capillaries) has been carried out in congestive splenomegaly occurring in active chronic hepatitis, hepatic cirrhosis and idiopathic portal hypertension. Comparisons have been made with control spleens surgically removed for accidental trauma. Red pulp volume enlargement appears to be associated with a progressive lengthening of arterial terminals, which present a length density similar to that of normal spleens. Moreover, a different rearrangement of the various components of the arterial tree is present: in particular, the percent and absolute volumes of arterioles and arterial capillaries show a higher increase than those of sheathed capillaries. The present study points out the involvement of arterial terminals in the pathological rearrangement of the red pulp in congestive spleens, so supporting the hypothesis that splenomegaly does not result simply from passive congestion.

Adult↗

Hairy-cell leukemia complicating coeliac disease: report of a case and discussion of possible pathogenetic mechanisms.

10-28% of the patients with chronic coeliac disease develop a second malignancy, such as non-Hodgkin's lymphomas, particularly of the histiocytic type, and adenocarcinomas. The second tumor may arise in the intestinal tract or in other organs. We describe here a patient who developed a tartrate-resistant, acid phosphatase-positive, hairy-cell leukemia after a history of chronic coeliac disease. In the literature, no similar case has been described as yet.

Celiac Disease↗

Histometric analysis of sheathed capillaries in congestive splenomegaly.

The structural rearrangement of human sheathed capillaries in congestive splenomegaly with hypersplenism has been evaluated by histometric analysis. In abnormal spleens the external diameter and the wall thickness were decreased, while the internal diameter was increased. Moreover, the total length and the absolute number of sheathed capillaries were increased, though not to the same high degree as the volume of the whole red pulp. Thus, in addition to the well-known changes of the sinuses, also the terminal arterial passages appear to participate in the morphological rearrangement of the red pulp in congestive splenomegaly.

Adolescent↗

Carotid wall as an isotropic mechanical system.

The morphological organization of the structural components in the dog carotid wall is investigated by X-ray diffraction and microscopic analysis. Histological analysis confirms an anisotropic morphology of smooth muscle cells and elastic fibers in the tissue. Collagen fibers, as revealed by X-ray diffraction technique, are organized in an isotropic network in the unstretched carotid media. Collagen fibers stretch without a preferential direction of orientation when a carotid segment is deformed in the physiological range under intraluminal pressure. A mathematical model which takes into account the isotropic distribution of the collagen fibers is developed. The validity of this model has been tested by computing several mechanical parameters using Anliker's data on the axial and radial oscillation obtained for carotids of living dogs. In spite of the anisotropic morphology of the main constituents of the carotid media layer, from a mechanical point of view the tissue can be considered as an isotropic material for the random distribution of the collagen fibers which represent the component of higher tensile strength.

Animals↗

[Vascular flow-regulating devices in the human kidney].

Small arterious and venous vessels of the juxtamedullary cortex of normal human kidney present wall formations regulating the blood flow. The arterious devices appear either as sphincterial rings at the origins of collateral branches of interlobular arteries, or as groups of myoepithelioid cells in the wall of small arteries immediately preceding the afferent arterioles. The venular devices consist of circular muscular thickenings repeated along the course of the vessel.

Adult↗

[The presence of arteriovenous anastomoses in the human kidney].

The microscopic observation of serial sections obtained from normal human kidneys allowed to demonstrate the presence of arteriovenous anastomoses in the juxtamedullary cortex. In particular one section is shown which clearly presents an anastomotic channel along with its connections to both an afferent arteriole and a venule.

Adult↗

[Mechanical properties of the human basilar artery].

The mechanical properties of the wall of human basilar artery have been determined by tension tests. The degree of orientation of collagen fibers inside the deformed arterial wall has been evaluated by the analysis of the mechanical results and by the X-ray diffraction pattern. The results show that the wall of the muscular arteries can be considered a "composite material" which mechanical properties, at high stress, are due mainly to the collagen fibers orientation.

Basilar Artery↗