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Biomedical subjects

G Ravichandran

Publications and source records attributed to G Ravichandran.

31 records · Page 2Linked to original sources

Survival following traumatic tetraplegia.

In a review of 166 male tetraplegic patients admitted over an eleven year period, there were four acute deaths. Three of the four were over the age of 60 at the time of injury. Of the remaining 162 patients, the whereabouts of 143 patients could be ascertained. Twenty-three were lost to follow up. Sixteen patients died during the period of follow up. There were no deaths among those tetraplegics who survived for at least 5 years after the injury. Respiratory infections were the commonest cause of death among tetraplegic patients. With improved primary care of the tetraplegic patient acute mortality can be reduced.

Adult↗

Upper lumbar spondylolysis.

Upper lumbar spondylolysis is rare and there are few reports which describe the condition. Three patients with upper lumbar spondyloysis, two of whom underwent surgical treatment, are reviewed. A radiological review of 205 patients with back pain attending a Back Research Clinic revealed three additional patients with symptomatic upper lumbar spondylolysis. clinical diagnosis of this condition is often difficult and the results of operation are unsatisfactory. It is more common among men and trauma appears to play a major role in the production of symptoms.

Adult↗

Spinal cord function in Paget's disease of spine.

The adverse influence of diminished spinal cord blood flow has been well documented. There is increased skeletal blood flow in Paget's disease of bone, with a corresponding reduction in the size of the anterior spinal artery. Use of salmon calcitonin results in rapid reduction in the bone perfusion. The recovery of cord function following calcitonin therapy in patients with paraplegia due to Paget's disease of the vertebral column is likely to be due to enhanced spinal cord perfusion.

Calcitonin↗

Paraplegia due to intervertebral disc lesions: a review of 57 operated cases.

In a review of 57 cases of paraplegia due to surgically confirmed disc protrusion (representing 0.9 per cent of all admissions to the National Spinal Injuries Centre), seven were in the cervical, 31 in the dorsal and 19 in the lumbar regions. Patients with dorsal disc protrusions treated by laminectomy had the worst neurological outcome. A recent decline in the incidence of neurological dysfunction following disc excision is noted and its probable causes discussed.

Female↗

Zygapophysial arthropathy. Intervertebral apophyseal joint arthropathy.

Normal saline injections into appropriate zygapophysial joints were carried out on low back pain suffers to reproduce the pain. Patients were selected on certain defined clinical criteria for inclusion to this pilot study. Only five out of ten patients reported accurate pain reproduction and these were thought to suffer from zygaphophysial arthropathy. It is argued that recognition of this condition will influence its management.

Adult↗

A radiologic sign in spondylolisthesis.

Isolated lateral deviation and rotation of a spinous process seen in anteroposterior radiographs of the lumbar spine seems to be associated with pathology in the pars interarticularis. This radiologic sign was present in 57 patients with spondylolisthesis and five cases of spondylolysis. It was absent in 165 patients with radiologically normal pars interarticularis. There were no false positives, but the sign could not be demonstrated in the radiographs of four cases of spondylolisthesis and one of spondylolysis. An explanation of the mechanism of this sign is offered.

Female↗

Spinal cord angioma--non-progressive disease?

In an analysis of 214 patients admitted to the Midland Spinal Injuries Unit with non-traumatic cord damage 18 patients had arteriovenous malformations (AVM of the cord. This paper describes the experience gained by this unit in the rehabilitation of these patients. A brief review of literature is included, essentially to highlight the relentless progress of the disease. The overall rehabilitation potential of these patients was poor. Fifty per cent of patients had further neurological loss during the follow-up period after the onset of paraplegia.

Adolescent↗

Traumatic single facet subluxation of cervical spine without neurological damage. A new clinical sign.

The vast majority of injuries to the cervical spine, unaccompanied by neurological deficit, escape diagnosis because of the minimal clinical symptoms associated with such injuries. For the same reason many of those who consult their doctors following such injuries, are not adequately investigated. This article presents a new clinical sign to recognise a certain type of cervical spine injury, and a simple way of documenting the observations. It is proposed that in the presence of this sign, adequate radiological investigations must be deemed mandatory to exclude bony injury to the cervical spine.

Cervical Vertebrae↗

Chymopapain chemonucleolysis. A preliminary report.

Twenty of 26 consecutive patients with sciatica caused by myelographically proven disc protrusions who were treated by chemonucleolysis with chymopapain made useful recovery. There were no major complications attributable to the procedure. Certain diagnostic and clinical criteria are described which appear to be important in producing a favorable result following chemonucleolysis.

Adult↗

Multiple lumbar spondylolyses.

Spondylolysis of more than one lumbar vertebra occurring in the same individual is rare. The incidence of multiple lumbar spondylolyses appears to vary between 1.2% and 5.6%. Most cases respond to conservative treatment. When surgery is indicated, it must be radical, and the fusion should include all the defects and the intervening normal vertebrae and the sacrum. The condition is more common among men, and trauma plays a major role in its initial appearance.

Adult↗