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Biomedical subjects

G Rahav

Publications and source records attributed to G Rahav.

At least 55 records · Page 3Linked to original sources
PubMed1991

Acceptance of mental retardation and help-seeking by mothers and fathers of children with mental retardation.

Help-seeking preferences of parents of children with mental retardation were examined. A specially constructed Acceptance of Retardation Scale was administered to 25 fathers and 25 mothers. Respondents were asked to consider a number of need situations associated with their child's retardation and rate the likelihood that they would try to help themselves or seek external help from various sources. Results showed that mothers and fathers may have different help-seeking patterns. The fathers' help-seeking behavior seems to be instrumental, whereas mothers seem to be affected by ego considerations. Several demographic correlates of help-seeking behavior were also collected. Implications were discussed.

Adaptation, Psychological↗
PubMed1990

Development of sensitive methods for the detection of mycobacteria by DNA probes.

A sensitive method allowing the detection of mycobacteria by DNA probing has been developed. Besides the choice of a relevant probe encoding for part of the ribosomal RNA genes, the critical step allowing this high sensitivity was the method by which mycobacteria were lysed. Sonication of mycobacteria in the presence of chloroform followed by dot blot by this lysate gave the highest sensitivity in the detection of sequences homologous to the DNA probes.

Cloning, Molecular↗
PubMed1990

Relationship between the acetylator phenotype, plasma sulfapyridine levels and adverse effects during treatment with salicylazosulfapyridine in patients with chronic bowel diseases.

We examined 122 patients with inflammatory bowel disease treated with salicylazosulfapyridine. Forty-two (34.5%) had adverse effects that led to discontinuation of therapy in 14 (11.5%). In 33 patients the effects appeared to be dose dependent. The plasma sulfapyridine levels in patients exhibiting gastrointestinal side effects were significantly higher than in patients with no adverse effects (41.0 +/- 20.3 and 23.8 +/- 14.8 micrograms/ml respectively, P less than 0.001). Plasma sulfapyridine levels were significantly higher in slow than in fast acetylators (31.5 +/- 17.1 vs. 22.2 +/- 17.1 micrograms/ml). Slow acetylators had three times as many side effects as fast acetylators; however this difference was not statistically significant.

Acetylation↗
PubMed1989

Prolonged pyrexia and lung metastases. A rare presentation of an occult epithelioid sarcoma.

A 31-year-old patient presenting with fever of unknown origin, night sweats and weight loss, associated later with pulmonary nodules, is described. Multiple invasive diagnostic procedures, including exploratory laparotomy and open-lung biopsy, suggested a benign inflammatory granulomatous disease. Metastatic epithelioid sarcoma was ultimately diagnosed after biopsy of an enlarging groin mass. Epithelioid sarcoma should be considered in the differential diagnosis of prolonged fever, associated with granulomas of obscure etiology.

Adult↗
PubMed1989

Sensation seeking, state and trait anxiety, and depressive mood in adolescent substance users.

The following hypothesis has been tested: sensation seeking, A-state and A-trait, and depressive mood should positively affect adolescent substance use. The personality variables and alcohol and drug use were assessed among 1,900 Israel adolescents, 14 to 19 years old. The major findings were as follows: (a) Sensation seeking and availability significantly affected the "ever" and "current" substance use among adolescents. On the other hand, contrary to our hypothesis, neither A-trait nor depressive mood significantly affected substance use. (b) A-State affected the use of alcoholic beverages and nonprescribed medications. (c) The data emphasized the significant role of availability of drugs in the understanding of adolescents' substance use. The implications of these findings for interventions among adolescents are discussed.

Adolescent↗
PubMed1989

Acute febrile neutrophilic dermatosis (Sweet's syndrome).

We describe a patient who displayed the classic features of acute febrile neutrophilic dermatosis (Sweet's syndrome): sudden onset of erythematous plaques, fever, arthritis, and characteristic histologic findings. Unusual findings in her case were the localization of the lesions mainly on the legs, absence of leukocytosis and preceding illness, and marked neutrophilic infiltration in the subcutis. In addition, the fever and eruption subsided on the day the results of pathologic examination were available, making any treatment unnecessary. The short course of the disease in this patient suggests the possibility of postponing steroid treatment for one week in all patients with acute febrile neutrophilic dermatosis.

Acute Disease↗
PubMed1989

Suicide and attempted suicide: their relation to subjective social stress indicators.

We investigated the relationship between the subjective perception of external stress and suicidal behavior, using a stress model which indicated that the probability of suicide and attempted suicide, as a reaction to stress, increases when social support systems fail or malfunction. We conceived the subjective perception of social stress as expressions of worry or dissatisfaction regarding cardinal life domains such as economic, security, or political situations. We defined support systems in terms of national solidarity expressed as positive (or improved) attitudes regarding the relations between various segments of the population, and we derived the data regarding the subjective indicators from continuing surveys of representative samples of urban Israeli population during the years 1967 through 1979. Eight stress indicators and three solidarity indicators were included, and our findings generally supported the theoretical model. However, the findings regarding men conformed best in relation to suicide, whereas those regarding women confirmed the theoretical model mainly in relation to attempted suicide. Contrary to the model, female suicide rates decreased in times of stress. Feelings of social solidarity in the population were found to reduce suicidal behavior of both men and women.

Cross-Sectional Studies↗
PubMed1987

Reversible busulfan-induced ovarian failure.

A 26-yr-old woman with chronic myeloid leukemia developed busulfan-induced ovarian failure. The ovarian failure was manifested by amenorrhea and climacteric symptoms and was verified by elevated plasma levels of luteinizing and follicle-stimulating hormones concomitant with low 17 beta-estradiol levels. The amenorrhea proved to be reversible when, during hematological relapse one year later, the patient was found to be four months pregnant. The busulfan which she was receiving at that time was stopped and amniocentesis revealed a normal karyotype. The remainder of the pregnancy was unremarkable and was terminated by the normal delivery of a healthy child.

Adult↗