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Biomedical subjects

G Ragni

Publications and source records attributed to G Ragni.

At least 73 records · Page 4Linked to original sources
PubMed1981

[Indications for radiotherapy of lung cancer in the light of its clinical reality].

Reference is made to a large series and the literature in an attempt to single out cases where radiation management is indicated in the curative, palliative and anatalogic treatment of lung cancer, an in association with other therapies. It is pointed out that each case much be examined on its merits in the light of the histological type, the extent of the process, and its possible metastasis. The conclusion is drawn that radiotherapy plays a useful part in the albeit slight increase in survival of lung cancer patients under acceptable general conditions.

Humans↗
PubMedDate not supplied

Post-coital test in subfertile men.

Twenty-two patients with border-line spermiograms (moderate oligoasthenozoospermia or asthenozoospermia) were studied by the post-coital test (PCT) to determinate the behaviour in vivo of semen with modest dysspermia (spermatozoa counts between 10 and 20 million/ml, with 20-40% forward motility). All the female partners were normal morphologically and functionally. The PCT were always carried out when the cervical mucus was favorable (mean score 12.2-12.3) and the endocervical pH was 7.25-7.30. The positive results for the asthenozoospermic semen samples were 6.75% and for the oligozoospermic one 10%, when the classification were based on the W.H.O. criteria. When the semen samples were classified according to Kremer's criteria positive results were found in 37.5% and 40% of the cases respectively. The effects of both cervical mucus properties and pH on the results of the PCT were found to be important. The high percentage of the favorable results emphasizes the usefulness of completing studies of border-line spermiograms with an in vivo test, since it is difficult to define normality and predict the fertility potential from semen examination alone.

Cervix Mucus↗
PubMedDate not supplied

Abnormal semen quality and low serum testosterone in men with inflammatory bowel disease treated for a long time with sulfasalazine.

Our purpose was to study the effects of long-term salazopyrine treatment on male fertility. Seven patients, 21-37 years old, who had been treated for ulcerative colitis with 3 g/day of salazopyrine for more than 6 months, were examined. All their semen samples showed abnormal sperm motility (17% +/- 9.3) and abnormal morphology (36.3% +/- 14.4) with the predominance of large-headed spermatozoa. The endocrine picture and pituitary reserve were evaluated by GnRH and TRH tests. The basal values of testosterone were lower than the normal in our laboratory (greater than 3 ng/ml) and significantly lower (2.4 +/- 0.7 ng/ml, p less than 0.025) than in the control group (fertile men). LH was significantly higher (9 +/- 2 mIU/ml, p less than 0.005) but still within the limits of normal. The responses of FSH and LH to GnRH and of PRL to TRH were normal. The mechanisms by which salazopyrine may affect fertility are discussed.

Adult↗