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Biomedical subjects

G R Cumming

Publications and source records attributed to G R Cumming.

At least 37 records · Page 2Linked to original sources

Evaluation of the Canadian Home Fitness Test in middle-aged men.

The Canadian Home Fitness Test (CHFT) and the Bruce treadmill test were performed by 230 men aged 45 to 69 years. Because of inaccuracies in the counting of heart rates, less was known about the fitness of the men after testing than before. In addition, inaccuracies in the test record and design were uncovered. A more accurate estimate of fitness could be obtained when the subjects' own rating of exertional intensity was substituted for heart rate counting. The CHFT is a marketing tool of Health and Welfare Canada that may be useful in selling fitness, but as a measure of fitness in Canadian homes it is likely to be misleading.

Aged↗

Hemodynamics of supine bicycle exercise in "normal" children.

Sixty children age 5 to 16 years with normal or nearly normal hearts performed submaximal and maximal supine bicycle exercise. Submaximal cardiac output was linearly correlated with work load (r = 0.80). After 2 minutes' exercise cardiac output was over 90 per cent of the value for 6 minutes' exercise. Maximal cardiac index was 10.1 +/- 1.8 for boys and 8.6 +/- 1.8 L. per minute per square meter for girls. Stroke volume was highest during the recovery period after maximal exercise. Pulmonary artery PO2 fell to 24 mm. Hg, oxygen saturation to 33 per cent, and pH to 7.21. During maximal exercise mean pulmonary artery pressure was 24 +/- 5 mm. Hg and mean brachial artery pressure was 113 +/- 8. There were no major differences between children aged 5 to 9 years of age and those 10 to 16 years, except for higher hemoglobin values in postpubertal children.

Adolescent↗

Constrictive pericarditis with dwarfism in two siblings (mulibrey nanism).

Two siblings with marked dwarfism, now 11 and 19 years of age, have been followed from infancy. The girl had frequent episodes of pneumonitis and presented at age 4 years with hepatic enlargement and ascites which proved to be due to constrictive pericarditis. The boy presented with growth failure and pseudohydrocephalus. He had fibrous dysplasia of the tibia and a pathologic fracture; acute hepatic congestion followed physical activity at age 13 years and led to the diagnosis of constrictive pericarditis. Muscle function was normal, there was no evidence for a primary liver disorder, and mental development was normal so that the coined word "mulibray" seemed inappropriate. Pericardiectomy produced only partial improvement; both patients have hepatic enlargement and continue to need diuretics. A third patient with dwarfism, frequent respiratory infections, and pericardial calcification has certain features of the syndrome.

Adolescent↗

Second heart sound after pulmonary arterial banding operation.

After a pulmonary arterial banding procedure the phonocardiograms of 38 patients were correlated with haemodynamic and angiographic findings. Twenty-four patients had uncomplicated ventricular septal defect, 2 had single ventricle, 5 had transposition of the great arteries, 5 had atrioventricular canal defects, and 2 had coarctation of the aorta and ventricular septal defect. P2 was separated from A2 by less than 40 ms in 10 of the 11 patients with high pulmonary vascular resistance. Of 27 patients with nearly normal pulmonary vascular resistances and distal pulmonary artery pressures less than 50/20 mmHg (6-7/2-7 kPa), 24 had A2-P2 intervals of over 40 ms. A narrow A2-P2 interval with a satisfactory band was found in 2 patients with large right-to-left shunts. A2-P2 interval did not change appreciably with age, and this measurement is a useful guide as to the effectiveness of pulmonary artery banding by one year after operation. If this interval is less than 40 ms, repeat catheterization should be carried out as such patients may have persisting pulmonary hypertension and an increased pulmonary vascular resistance.

Age Factors↗

Electrocardiographic changes during exercise in asymptomatic men: 3-year follow-up.

Electrocardiographic (ECG) changes during maximal bicycle exercise and risk factors for coronary heart disease (CHD) were studied in 510 male civic employees who were followed for 3 years. Clinical CHD developed in 15 (24.6 percent) of the 61 men with an ischemic exercise ECG on the initial examination and in 11 (2.4 percent) of the 449 subjects with a normal initial exercise ECG. A normal maximal exercise ECG is no guarantee that severe CHD does not exist and that a subject will not soon sustain major myocardial damage; and an ischemic exercise ECG does not necessarily indicate underlying CHD. In the former group angina was the most frequent clinical CHD episode; in the latter group, infarction. Among those with an abnormal initial exercise ECG, CHD was most likely to develop in association with a poor exercise capacity. Subjects with subsequent clinical CHD and those with abnormal ECGs after 3 years tended to have a higher frequency of risk factors; subjects whose abnormal ECGs reverted to normal after 3 years tended to have a lower frequency of risk factors.

Adult↗

Obstruction of superior vena cava after the Mustard procedure for transposition of the great arteries. Conservative management of chylothorax.

Chylothorax may be produced by superior vena cava (SVC) obstruction, a recognized complication of the Mustard operation for trasposition of the great arteries. The chylothorax may be reduced by keeping the subject in the upright position. Conservative management is an alternative to repeat operation. This syndrome must be recognized, as it can be confused with congestive heart failure. Severe chylothorax may develop insidiously because of progressive SVC obstruction after the immediate postoperative period.

Angiocardiography↗

Acute rheumatic fever.

While rheumatic fever is relatively uncommon except where there are poor and crowded living conditions, sporadic acute attacks continue to occur in a family or pediatric medical practice. The physician's role in management of the sore throat in the diagnosis of suspected cases of rheumatic fever and in follow-up for continued prophylaxis is discussed. The frequency of admissions and presenting features of 159 patients with acute rheumatic fever is reviewed. Continued surveillance is required if we are to achieve a further reduction in attack rate and complications.

Acute Disease↗

Exercise ECG changes in normal women.

Submaximal and/or maximal exercise was carried out by 357 women without a history of cardiovascular disease, using a bicycle ergometer and/or treadmill while monitored by a bipolar ECG lead CM(5). In 40- to 60-year-old women the incidence of an ischemic ECG pattern during or after exercise ranged from 20 to 50%. Because clinical coronary disease can be expected in less than 10% of normal women followed for 16 years, most of these ECG changes were not considered to be due to occult coronary disease. At the present time exercise ECG changes in women cannot be used with any reliability as an aid in the diagnosis of chest pain or in screening normal female populations for coronary heart disease.

Adipose Tissue↗