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Biomedical subjects

G R Adams

Publications and source records attributed to G R Adams.

At least 55 records · Page 3Linked to original sources
PubMed1988

Sequence-specific binding of luzopeptin to DNA.

We have examined the binding of luzopeptin, an antitumor antibiotic, to five DNA fragments of varying base composition. The drug forms a tight, possibly covalent, complex with the DNA causing a reduction in mobility on nondenaturing polyacrylamide gels and some smearing of the bands consistent with intramolecular cross-linking of DNA duplexes. DNAase I and micrococcal nuclease footprinting experiments suggest that the drug binds best to regions containing alternating A and T residues, although no consensus di- or trinucleotide sequence emerges. Binding to other sites is not excluded and at moderate ligand concentrations the DNA is almost totally protected from enzyme attack. Ligand-induced enhancement of DNAase I cleavage is observed at both AT and GC-rich regions. The sequence selectivity and characteristics of luzopeptin binding are quite different from those of echinomycin, a bifunctional intercalator of related structure.

Antibiotics, Antineoplastic↗
PubMed1987

The interactional teaching patterns of mothers and fathers with their popular, moderately popular, or unpopular children.

The interactional teaching strategies of mothers and fathers toward their sociometrically determined popular, moderately popular, or unpopular children, and children's responses to them were examined during a structured puzzle task in a laboratory setting. Parents of popular children used more explanations in aiding their children to complete the puzzle task than parents of moderately popular or unpopular children. Mothers were more likely to offer suggestions, use explanations, and ask questions during the puzzle task than fathers. Analysis of children's responses revealed that popular children were more likely to ignore imperatives by their parents compared with unpopular children, while unpopular children showed a tendency to be more cooperative following imperatives by parents than popular children. Finally, popular children were less likely to ignore but were more likely to go off task following suggestions by parents than either unpopular or moderately popular children. The data are discussed with respect to the possible link between parental socialization patterns and children's popularity in the peer group and the need to consider the interaction patterns in both the peer and parent-child systems for intervention purposes.

Adult↗
PubMed1985

Family correlates of female adolescents' ego-identity development.

Past research has suggested that parents may contribute to the positive development of their daughter's identity formation. Theoretical notions from both social learning and symbolic interaction indicate that parents can either facilitate or hinder positive growth. Therefore, to test the predictions that (a) more mature (moratorium and achieved) identity status parents would have daughters with more mature identities, and (b) that both positive and negative parenting styles can be detected to differentiate between less (diffused and foreclosed) and more mature identity status youths, 45 families (145 subjects) were assessed on parent-child relations and identity status formation. In contrast to much past research, parent-child relations were assessed from both the adolescents' and the parents' perspectives. The findings indicate that parental identity status formation may have an effect on the adolescent's identity formation and that parent-child relations differentiate between less and more mature female adolescent identities.

Adolescent↗
PubMed1985

Homeless adolescents: a descriptive study of similarities and differences between runaways and throwaways.

A sample of 43 homeless adolescents was categorized as being either runaways, throwaways, or societal rejects. Comparisons of these categories of homeless youths were completed to assess the descriptive utility of internal social control, strain, and psychopathological theory in making distinctions between various homeless adolescents. Descriptive data support the view that control and psychopathology perspectives provide some promise for understanding differing types of runaway adolescents. Sex differences between runaway and throwaway youths were explored. However, few sex X type of homeless adolescent interactions were observed. Implications for secondary prevention, based upon these data, are offered.

Adolescent↗
PubMed1984

Ego identity status, conformity behavior, and personality in late adolescence.

Three related studies were completed to test the predictive relation among identity status, personality, and conformity behavior. The investigations were undertaken to replicate the earlier research findings of Toder and Marcia (1973). As predicted in Study 1, personality differences were found for both sexes. However, no relation was observed between identity status and conformity on the Asch task. Study 2 was completed to confirm the reliability of the identity status measure. Finally, in Study 3 four measures of conformity behavior (peer assessments, an experimental task, two self-report scales) were completed by college students of diffusion, foreclosure, moratorium, and identity-achievement statuses. Diffusion students were most influenced by peer pressure conformity, whereas identity-achievement students were most likely to report engaging in conformity behavior for achievement gains. Although earlier research by Toder and Marcia (1973) was not replicated via the Asch conformity task, the third study does support a predicted relation between identity and conformity behavior.

Adolescent↗
PubMed1981

A parenting group in general practice.

We describe the organization and experience of a discussion-support group for young mothers. The group, of seven women, met on 21 occasions over a period of six months. We found that certain themes and anxieties to do with parenting recurred and that discussing topics within the group was of help to the participants.

Child↗
PubMed1980

Divorce, single parenting, and child development.

Application of "crisis" and "social facilitation" theory to program intervention with preschool-age children was undertaken to asses the effects of a preschool education experience on recovery of psychological functions following divorce. A pretest-posttest control group design was completed using single-parent (n = 7) and two-parent (n = 8) children in an educational setting as the treatment groups and two-parent (n = 8) children at home as the control. Maternal reports on self-assesed childrearing and child's behavior were obtained during an interview, while intellectual assessments and observational data on social behavior were collected by trained observers and teachers. Little evidence could be noted that suggested weakened mother-child interaction as a function of divorce. Crisis intervention was observed to be an effective technique in assisting single-parent children toward cognitive recovery. However, it remains unclear whether social behavioral problems of single-parent children were positively affected by the crisis intervention program.

Child Development↗
PubMed1978

Physical attractiveness and personality development.

A test of the relationship between physical attractiveness and ego development was completed through an interview study of 294 men and women college students. Ss responded to personality measures assessing identity formation, locus of control, and ego functioning and were rated on facial attractiveness and body form scales. Contrary to the physical attractiveness stereotype, attractive and unattractive Ss did not differ in their personality styles.

Beauty↗