RE: MJ Krahn, NM Pettigrew, TE Cuddy. Unusual side effects due to warfarin. 1998; 14:90-3.
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Biomedical subjects
Publications and source records attributed to G Quenneville.
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This report of a patient with Peutz-Jeghers syndrome is unusual in a number of ways: the patient, a 49-year-old woman, was first seen with deep thrombophlebitis of the leg which appeared to be part of a paraneoplastic syndrome. The patient had an adenocarcinoma originating in a hamartoma of the terminal ileum, with ovarian and lymph-node metastases. During the course of the disease the patient was found to have metastatic disease in the cervical lymph nodes which responded, temporarily, to chemotherapy. The authors review the literature on metastatic Peutz-Jeghers syndrome. Although the rate of metastatic disease is low, they believe that all patients with Peutz-Jeghers syndrome deserve a close long-term follow-up.
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A case is presented of lower digestive bleeding, caused by a fistula between a right iliac artery aneurysm and the sigmoid colon. Particular aspects of this unusual fistula are discussed from a diagnostic and therapeutic point of view.