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Biomedical subjects

G Preti

Publications and source records attributed to G Preti.

At least 91 records · Page 5Linked to original sources
PubMed1979

Steroid analysis of human apocrine secretion.

Analysis of the secretion of the human apocrine gland has shown the presence of dehydroepiandrosterone and androsterone sulfates, two androgen steroids previously identified in axillary sweat. These steroid sulfates were characterized by the gas chromatographic/mass spectrometric analysis of the odorous steroids formed on direct injection of the apocrine secretion into the host gas chromatographic injector. No spectral evidence was found for the presence of the delta16-androgen steroids which have axillary-like odors and have also been reported in axillary sweat. Cholesterol was the major steroid component of the secretion.

Adult↗
PubMed1979

Alterations in the organic compounds of vaginal secretions caused by sexual arousal.

The low-molecular weight organic constituents of human vaginal secretions from normally cycling subjects were analyzed both before and after sexual stimulation. Gas chromatography and combined gas chromatography-mass spectrometry were employed in the analyses of the secretions. Consistent increases were noted for a number of the lipid constituents of the secretions, suggesting that they are derived at least in part from the plasma and transude into the vaginal lumen during arousal. In addition, the increases in the concentrations of glycerol and stearic acid with respect to baseline levels were significant (P is equal to and less than 0.05). Compounds which are produced intravaginally appear to decrease in concentration during the arousal interval because of dilution by the transudate. No consistent qualitative changes were noted in the secretion.

Acetates↗
PubMed1976

Volatile constituents of human vaginal secretions.

Vaginal secretions were serially studied for 44 ovulatory cycles from 12 patients by means of combined gas chromatograph--mass spectrometry to identify small organic volatile compounds. In 10 of these cycles ovulation was documented with plasma radoioimmunoassays for progesterone, estrogens, and LH. These secretions contain a complex mixture of acids, alcohols, hydroxyketones, and aromatic compounds. Lactic acid, acetic acid, and urea were found to be present in all patients and underwent sharp cyclical variations in concentration with maxima in all patients occurring at midcycle. Small-chain, volatile C2-C5 aliphatic acids which have been shown to induce mating behavior in male rhesus monkeys were found in only four patients. In these patients the above acids were found predominantly at midcycle and during the luteal phase.

Alcohols↗
PubMed1976

Beta-methylcrotonic aciduria associated with lactic acidosis.

A patient is described in whom lactic acidosis of very severe degree was found to coincide with the presence of beta-methylcrotonic acid and rho-hydroxyphenyllactic acid in urine in large amounts, while beta-hydroxyisovaleric acid was found to be a relatively minor excretion product. Beta-methylcrotonic acid is demonstrated, for the first time, to be present in blood and CSF. These findings are discussed in relation to the patients previously reported to have beta-methylcrotonylglycinuria and raise the possibility that our patient's organic aciduria may be secondary to acquired disease rather than to an inborn error of metabolism.

Amino Acids↗
PubMed1976

[Roengenocinematographic studies on the stability of the total prosthesis during mastication].

Two upper and lower full dentures of the same individual were subjected to stability tests. One of the dentures was done in a conventional way, while the other was mounted, using the author's words: "in a multilocal and autonomous stability". Both dentures were analyzed clinically, on the articulator, radiographically, and roentgencinematographically during mastication. Particularly in the latter examination it could be shown that the multilocally and autonomously stable denture offered more stability during mastication.

Aged↗
PubMed1975

Changes in the intensity and pleasantness of human vaginal odors during the menstrual cycle.

Men and women estimated (by the method of magnitude estimation) the pleasantness and intensity of the odors of vaginal secretions sampled from consecutive phases of 15 ovulatory menstrual cycles of four women. On the average, secretions from preovulatory and ovulatory phases were slightly weaker and less unpleasant in odor than those from menstrual, early luteal, and late luteal phases. However, considerable variation in odor patterns was present across cycles from the same donor, as well as across cycles from different donors. These results indicate that human vaginal odors change slightly in both pleasantness and intensity during the menstrual cycle, but do not support the notion that such odors are particularly attractive to humans in an in vitro test situation.

Animals↗
PubMed1975

[Relations between protidopoiesis and biological transmethylations: action of S-adenosylmethionine on protein crasis in chronic hepatopathies].

After a diffuse introductory discussion on S-adenosylmethionine methyltransferase activity, the results of an experimental trial carried out on 70 hospitalized patients with chronic hepatitis either persistent or aggressive, and with hepatic cirrhosis at various degrees, are reported. A first group of patients was treated with SAMe (S-adenosylmethionine) intravenously administered for 20 days at two daily doses of 15 mg. The second group was instead-receiving, still by i.v. route, 20 mg of fructose-1-6-diphosphage sodium salt, as a drug for comparison given twice a day at the doses of 2.5 over a 20 days' period. The protidemia picture and in particular the albuminic fraction, generally altered in all the cases under study, have been rapidly and significantly restored only in the group of patients treated with SAMe this indicating the efficacy of this molecule on the liver function.

Blood Proteins↗