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Biomedical subjects

G Prabhakar

Publications and source records attributed to G Prabhakar.

50 records · Page 3Linked to original sources

Nonischemic intussusception in childhood.

The classical presentation of intussusception consisting of severe abdominal pain, bloody stool, and a palpable abdominal mass leads to the correct diagnosis in majority of the patients. However, an atypical presentation often results in a delayed diagnosis as is commonly seen in nonischemic intussusception. The nonischemic intussusception is a distinct clinical entity that is characterized by a long history of less severe symptoms commonly noticed in older children. The incidence of diarrhea in this group is higher than in the acute variety of intussusception. This variant of intussusception requires a high degree of suspicion for the diagnosis in atypical clinical presentation. The present study summarises our experience treating 31 such cases of nonischemic intussusception during a period of 25 years from 1966 to July 1990.

Child↗

Total cavopulmonary connection for right ventricular endomyocardial fibrosis.

Endomyocardial fibrosis is an endemic problem in tropical countries and is characterised by ventricular cavity obliteration, decreased ventricular compliance, and atrioventricular valve regurgitation. We report on a patient with right ventricular endomyocardial fibrosis resulting in obliteration of the cavity and tricuspid regurgitation treated successfully by total cavopulmonary connection and exclusion of the right ventricle.

Adult↗

Therapeutic and diagnostic role of bronchoscopy in pediatric age group.

Two hundred and seventy five cases were evaluated bronchoscopically for various respiratory conditions. In 140 cases, a foreign body and in 30 cases mucus plug was removed. In 47 cases there was inflammation of the tracheobronchial tree. Forty patients with empyema thoracis were evaluated bronchoscopically because of persistence of bronchopleural fistula or continued pus discharge from intercostal tubes not responding to the routine treatment. The purpose of the article is to stress the therapeutic as well as diagnostic aspect of bronchoscopy for various respiratory conditions in pediatric age group.

Bronchoscopy↗

Spontaneous gastrointestinal perforation in the neonate.

Twenty seven cases of spontaneous gastro-intestinal perforation were treated from 1981 to 1990. Four perforations were in the stomach, 17 in the small bowel and seven in the large bowel. One of them had dual perforation, one in the stomach and another in the duodenum. The exact etiology remained obscure. Various factors observed were maternal obstetric complications, prematurity and perinatal asphyxia. Stress should be laid on early diagnosis by following up 'at risk neonates' thus, giving a better overall survival rate.

Female↗

Pulmonary artery versus left ventricular venting: a radioisotope study of left ventricular function.

Radionuclide measurements of ejection fraction were used to assess immediate and late postoperative ventricular function after the use of either a pulmonary artery vent (group A) or a left ventricular vent (group B) in 20 patients undergoing aortic valve replacement for pure aortic stenosis. Ten patients were included in each group and anesthetic techniques, patient management, and septal temperatures were similar in all cases. No significant difference was found between the preoperative and immediate or 6-week postoperative ejection fractions, either taken overall or between the two groups (p greater than 0.05; Student's t test). No correlation was found between cross-clamp time, bypass time, or the occurrence of ventricular fibrillation and the immediate postoperative ejection fraction (p greater than 0.05; Student's t test). There was no significant difference in the incidence of ventricular fibrillation after each type of vent had been used (chi 1(0) = 3.32; p greater than 0.05). We did not demonstrate any abnormalities in regional wall motion associated with apical insertion of a left ventricular vent, and conclude that pulmonary artery and left ventricular vents are equally satisfactory in terms of postoperative ventricular performance.

Adult↗

The use of atenolol in the prevention of supraventricular arrhythmias following coronary artery surgery.

Sixty patients undergoing coronary artery bypass surgery were studied prospectively in order to investigate the effect of a cardioselective beta-blocker on the incidence of postoperative supraventricular arrhythmias. Patients with good left ventricular function were randomly divided into two groups: 30 patients treated with atenolol and 30 patients acting as controls. Atrial fibrillation was seen in 11 patients and frequent premature atrial extrasystoles were noted in one. Eleven (37%) patients in the control group experienced arrhythmias whilst atenolol significantly reduced this incidence to 3% (one patient), P = 0.001. There was no significant relationship between the development of supraventricular arrhythmias and the following variables: age, sex, severity of preoperative symptoms, previous myocardial infarction, extent of coronary artery disease, technique of myocardial preservation used, ischaemic time, number and site of saphenous vein grafts, endarterectomies performed and perioperative serum potassium levels. It is concluded that the use of atenolol (started 72 h before operation) is effective in reducing the incidence of supraventricular arrhythmias following elective coronary artery bypass operations in patients with good left ventricular function.

Angina Pectoris↗

Benign mediastinal teratoma causing pericardial tamponade and pleural effusion.

Mediastinal teratomas are known to adhere to and penetrate the pericardium, but perforation and tamponade are uncommon. We present a patient who developed a life-threatening pericardial tamponade and pleural effusion, whose life was saved by timely surgery. We believe this to be the third successfully treated patient and the first to be reported from Great Britain.

Adult↗

Colorectal carcinoma.

Two rare cases of colorectal adenocarcinoma seen during the last 3 years in children under 10 years of age are reported. To improve survival, emphasis is given on its early diagnosis by a thorough examination and investigation of the child in every case of prolonged bleeding per rectum, diarrhoea and other non specific abdominal symptoms.

Adenocarcinoma, Mucinous↗

Toxoplasmic retinochoroiditis and hydrocephalus.

A child presenting with hydrocephalus with extensive inactive retinochoroiditis and his mother with a healed toxoplasmic scar is being discussed. Maternal ocular examination in each case of hydrocephalus is recommended, as uveitis work up of the child is often unrewarding.

Chorioretinitis↗

Esophageal atresia: tragedies and triumphs over two decades in a developing country.

During a period of two decades, 1972-1991, 303 patients with esophageal atresia and/or tracheo-esophageal fistula were treated at the department of Pediatric Surgery, SMS Medical College, Jaipur, India. More than half of our patients fall into Waterston's risk category C. To evaluate the improvement in our results, the patients were divided into four phases of 5 years each. Over the period of observation, the incidence of new cases as well as the number of associated anomalies has considerably increased. With time, more patients are being diagnosed and referred early for treatment. This has resulted in more patients being treated by primary repair with or without a gastrostomy. Extrapleural approach and single layer end-to-end anastomosis has been practised in all cases. Results have shown a steady improvement primarily because of early recognition, improved perioperative care and newer antibiotics. Although postoperative pulmonary complications and anastomotic leak have shown a decreasing trend, but the presence of severe associated anomalies, pulmonary complications and sepsis still remain the major killers in our set-up. Although our results may not match those from the developed countries, we have still come a long way, improving our overall survival rate of 4.6% in 1972-76 to 45.7% in 1987-91. Through the present article, we wish to highlight the practical problems faced in the management of these patients in underprivileged developing countries.

Developing Countries↗