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Biomedical subjects

G Pozzessere

Publications and source records attributed to G Pozzessere.

46 records · Page 3Linked to original sources
PubMedDate not supplied

Brainstem auditory evoked potentials in toxic, metabolic and anoxic coma.

The aim of this study was to evaluate the efficacy of brainstem auditory evoked responses as a prognostic tool in conditions of coma which interfere with cerebral metabolism. Thirteen patients in coma resulting from different systemic disorders (barbiturate intoxication, cardiac arrest, chronic hepatic insufficiency) were included in the study. Brainstem auditory evoked potentials were recorded and patients were graded according to the results. When used in conjunction with other clinical parameters (Glasgow Coma Scale), brainstem auditory evoked potentials provided a more reliable prognostic tool than the traditional EEG exam alone. A good correlation was found between electrophysiological data and clinical outcome not only in barbiturate (toxic) coma, but also in hepatic (metabolic) coma. Of particular significance was the disappearance of the components which follow wave III (grade 2), leading to a fatal outcome in all three patients in hepatic coma.

Adult↗
PubMedDate not supplied

[Longitudinal study of evoked responses (VEP, BAEP, SSEP) in multiple sclerosis].

The Authors have examined 20 subjects affected by "possible" multiple sclerosis by means of a multimodal (VEP, BAEP, SEP) electrophysiologically evaluation longitudinally conducted during a time period of 1 year. The electrophysiological data obtained are related to the clinical picture, the disease's evolution, and to the adopted pharmacological therapy, in order to attempt a more precise diagnostic and prognostic assessment of these patients.

Adult↗
PubMedDate not supplied

Multimodal evoked potentials and CSF findings in the diagnosis of multiple sclerosis.

A group of 30 patients classified on clinical grounds as having definite (N = 16) or probable MS (N = 14) according to McAlpine's criteria, has been studied using multimodal recordings of evoked potentials (visual, auditory, and somatosensory) and examination of the cerebrospinal fluid (CSF) for oligoclonal bands and Link's Index. Evoked potentials examination proved extremely sensitive in discovering asymptomatic lesions of the central nervous system. CSF data, in particular the presence of oligoclonal bands, had a high sensitivity for MS. According to these electrophysiologic and immunologic results, we have reclassified our patients in conformity with the diagnostic criteria proposed by Bartel. The combination of electrophysiological and CSF data, together with common clinical criteria, led to greater diagnostic accuracy, making it possible to reclassify most patients previously considered to have probable MS as having definite MS.

Adult↗
PubMedDate not supplied

[Syringomyelia. Clinical and neurophysiologic correlations (SEP) as a function of surgical treatment].

The authors have studied the somatosensory evoked potential (SEP) behavior following stimulation of upper and lower limbs in two subjects affected by syringomyelia. The patients were evaluated electrophysiologically before and after decompressive surgical treatment. The findings indicate a positive correlation between the SEP recordings and the role of CSF pressure in the central nervous system.

Adult↗
PubMedDate not supplied

Electrophysiological study in patients with chronic hepatic insufficiency.

Twenty patients affected by chronic hepatic insufficiency were studied by means of combined EEG, VEP and BAEP recordings. Subjects were classified, according to Parsons-Smith criteria, in grade 0 (without any clinical sign) and grade I (with minimal mental disturbances). In group 0 patients an elevated incidence of VEP alterations (40%) was observed, while EEG and BAEP recordings were less frequently (10%) abnormal. In group I patients a high degree of EEG (60%), VEP (70%) and BAEP (70%) abnormalities was found. Mean latency and interpeak interval values in group I patients were significantly prolonged if compared with the grade 0 and control groups. No correlations were found between electrophysiological data and blood biochemical parameters examined (ammoniemia, aminoacidemic pattern).

Adult↗
PubMedDate not supplied

Pattern visual evoked potentials in pseudotumor cerebri. A longitudinal study.

The prognosis of "benign" intracranial hypertension (Pseudotumor cerebri) is generally favorable. In fact, the resolution of the clinical picture is related to the disappearance of the increased intracranial pressure. However, sometimes an irreversible visual loss can occur. The authors studied, over a period of time, seven subjects suffering from pseudotumor cerebri utilizing pattern visual evoked potentials (VEPs). Five patients showed normal VEPs latencies that remained such in the successive controls. Two patients displayed pathological P100 VEPs latencies. Such findings tended towards a progressive transient improvement following decompressive lumbar puncture. The authors suggest that the VEPs alterations in these patients could be due to the association of general (increased CSF pressure) and local (malformations, scleral canalis constrictions) ocular factors. In these circumstances, the pattern VEPs recordings could be coupled with traditional methods of evaluation of visual pathway damage capable of provoking an irreversible compromission of the visual function.

Adolescent↗
PubMedDate not supplied

Electrophysiological (BAEPs) changes in subacute sclerosing panencephalitis.

Over a period of time, the authors have studied a case of subacute sclerosing panencephalitis (SSPE), by means of brainstem auditory evoked potentials (BAEPs). The observed abnormalities of the conduction time along the early auditory pathways appeared to be related to the clinical picture; in fact, during periods of transitory clinical improvement these abnormalities were less evident. In addition, the encountered electrophysiological alterations consisted of a marked pathologic increase in the III-V interpeak latencies. The authors suggest that the BAEPs findings in their case could have been influenced by either unfavourable endogenous conditions (edema, electrolyte changes, etc.) or CNS segmental lesions due to focal viral distribution.

Adolescent↗
PubMedDate not supplied

Pattern visual evoked potentials and brainstem auditory evoked responses in uremic patients.

With the improvement of dialysis therapy and subsequent increase in the average lifespan of uremic patients more interest has been directed towards neurological complications induced by chronic renal failure. Twelve uremic patients were selected on the basis of negative neurological and psychiatric examinations. Electroencephalogram, pattern visual evoked potentials (VEPs) and brainstem auditory evoked responses (BAERs) were recorded in all patients. Pathological latency increases of VEPs in six patients and of BAERs in three patients had been observed. These findings have been related by the authors to the action of toxic substances or to the presence of minimal demyelinating lesions of CNS. Since these pathological findings were observed in patients who were normal at the clinical examination, it has been suggested that the evoked potentials recording might be a sensitive index of initial early lesions of the CNS in uremic patients (Acta neurol. belg., 1982, 82, 72-79).

Adult↗