[Letter: False hyperleukocytosis due to cryoglobulinemia].
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Biomedical subjects
Publications and source records attributed to G Potron.
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The authors studies in fluorescence microscopy and electronic microscopy the dysmorphic erythroblasts of a case of acute erythremia. They found evidence of granular fluorescence on the smears, corresponding to the presence of prophyrins and proteinaceous cristallin structures on the ultrathin sections. It seems to be possible to establish a morphologic correlation between the fluorescent granules and the cristallin structures. Thus, the hypothesis of poryphrins adsorption on cristallin structures may be proposed.
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In the esterasic dosage of plasminogen, the authors aim to determine the optimal ratio between the amount of streptokinase to add and of plasminogen itself. It is essential that the activator formation be reduced, which explains the dissociations obtained with other methods.
The esterase activity of thrombin and plasmin on artificial substrates was used to study the kinetics of these enzymes by Lineweaver and Burk's method. In the plasma of new-born infants, plasmin obtained from streptokinase has an avidity comparable with that in adults. Thrombin is obtained by the action of staphylocoagulase and taipan venom. Its avidity has important individual variations and is different from that in adults. An inhibitor is present both in the plasma and in the serum of the new-born. Fibrinogen was studied by variations in absorption of light during coagulation by thrombin. The abnormalities observed depend on the physical and clinical conditions of the medium (ph, osmolality). These characteristics depend on the age of the infant, but also seem to depend on the conditions of the sample and, in particular, on fibrinolytic reactions. The existence of foetal fibrinogen is discussed.
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