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Biomedical subjects

G Pickering

Publications and source records attributed to G Pickering.

44 records · Page 3Linked to original sources

Frail elderly, nutritional status and drugs.

This review focuses on the interactions between nutritional status and drugs in frail elderly persons. Impairment of nutritional status, a component of clinical presentation in the frail elderly, has a major impact on the pharmacology of many drugs devolving from the physiological alterations it generates. Food itself plays a central role in nutritional status and in possible interactions with drugs. Conversely, drugs have often, directly and indirectly, a deleterious effect on the nutritional state of the elderly. However, research in this domain is scarce, and future clinical studies will need to include more elderly and frail elderly individuals, to help clinicians to better understand these interactions.

Aged↗

Pain and Alzheimer's disease.

Literature on pain management in Alzheimer's disease is slowly emerging and this review deals with different aspects of pain in this growing population. Clinical pain, experimental pain and assessment of pain in cognitively impaired patients are presented. Treatment of pain is also discussed. This review calls for more studies and clinical trials with a view to improve the comfort and quality of life of patients suffering from Alzheimer's disease.

Aged↗

[Therapeutic drug monitoring: a challenge for biologists].

Therapeutic drug monitoring may be a precious help for the clinician especially if rigorously performed, and it is used for many drugs. The leading role of biologists in the development of new tests is strengthened by the coming-up of new drugs, the increasing demands for clinical trials to study the concentration-clinical effects of drugs and the development of pharmacogenetics. These represent stimulating challenges to optimise therapeutic drug monitoring and favour collaboration between biologists and clinicians so as to improve the care quality of the patient.

Biology↗