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Biomedical subjects

G Pfaff

Publications and source records attributed to G Pfaff.

At least 55 records · Page 3Linked to original sources
PubMed1984

[Gunshot injuries in peacetime and their therapy].

Between 1976 and 1982 46 patients with gunshot injuries (43 m., 3 f.) were seen at the University of Heidelberg Department of Surgery. Frequent causes of injury in 42 adults (40 m., 2 f.) and 4 children (3 m., 1 f.) were suicide attempts (19) and carelessness in the handling of shotguns (11). Criminal offence was related to nine injuries; no retrospective classification of the event causing the injury was possible in further seven cases. Affected in descending order of frequency were brain and lung (10 each), soft tissue of thigh (9), intraabdominal organs (5), heart (4), liver and bone (3 each), blood vessels (2) and facial skull, penis, buttock, neck and mediastinum (1 each). Six patients suffered from combined injuries, in three cases a combined abdomino-thoracic injury was seen. Whilst suicidal injuries of the skull are related to poor prognosis, other peacetime gunshot wounds are less problematic when compared to military gunshot wounds due to the lower speed of the projectiles. Therapeutic procedures follow the general rules of open treatment of injuries including prophylaxis against tetanus and botulism as well as systemic antibiotic therapy. In general abdominal and abdomino-thoracic gunshot wounds as well as vascular injuries require immediate surgical procedure. In isolated thoracic injuries a conservative approach may be justified depending on the situation. The same rule applies to fractures caused by gunshots.

Abdominal Injuries↗
PubMed1982

[More accidents due to daylight saving time? A comparative study on the distribution of accidents at different times of day prior to and following the introduction of Central European Summer Time (CEST) (author's transl)].

In the summer of 1980 for the first time clocks in the Federal Republic of Germany were advanced 1 h ahead of Central European Time (CET), which had been in use until then. In a sample of a total of 1070 accident patients, who had accidents on data pairs taken from the months of May 1979 (before the introduction of the so-called Central European Summer Time- CEST) and May 1980, comparable by day of the week, holiday, and weather conditions, and were seen at the University of Heidelberg Dept. of Surgery, a statistically significant increase in accident frequency between 7:30 p.m. and 5:30 a.m. was found when comparing the years 1979 and 1980 (P less than 0.05). At the same time, the services of the outpatient department were claimed to a greater extent in the evening and night time in 1980 than prior to the introduction of CEST. Since the sample must be considered comparably as to age and sex distribution as well as calendar days and climatic influence, and change in routine due to the adaptation to daylight saving time is discussed as the most probable reason for the observed increase in accidents. The influence of CEST apparently exceeds a short adjustment phase. Further studies are recommended to investigate a possible correlation between daylight saving time and an increased risk of accidents.

Accidents↗
PubMed1981

[Possibilities for the application of electronic data processing in surgical departments (author's transl)].

The primary precondition for the application of electronic data processing (EDP) are organisational measures including adequate personnel who are needed for preparatory work. Special documentation and coding systems must be introduced for the purpose of data preparation, whereby the size of the EDP equipment (hardware) depends on the problem to be tackled. The EDP programms (software) should be designed in such a way that every doctor is able to operate the EDP equipment even with little knowledge of data processing. Equipment ranges from minicomputers and centralized computer systems to integrated information systems. Whereas today well-designed application models for minicomputers already exist, the integrated information system is still in a development stage.

Computers↗
PubMed1977

[CEA blood level in patients with Crohn's disease with reference to localization, duration and severity of the disease].

CEA-serum-levels were determined in 24 patients with Crohn's disease over a period up to 35 months. 13 patients showed elevated CEA-Levels (greater than 3 ng/ml). A positive correlation between the extent of the lesion and the CEA-serum-level could be demonstrated. This correlation could not be demonstrated in regard to the duration of the disease. The attempt to utilize CEA-serum-levels for the estimation of the activity of Crohn's disease showed a good correlation between the activity and CEA-levels in a few cases; the activity was measured by means of the Crohn's Disease Activity Index (CDAI), which was recommended in the National Crohn's Disease Study in the United States.

Adolescent↗
PubMed1976

The incidence of epistaxis in racehorses in South Africa.

In South Africa 2,41% of horses bleed in a race. If all raced until they were 7 years old probably another 2,12% would bleed. Many others bleed after the race or during exercise or at rest. The incidence of epistaxis is significantly greater in geldings than in females and uncastrated males (P less than 0,001). There is an age distribution of bleeding which is highest at 4 years and lowest at 2 years of age (P less than 0,001).

Age Factors↗
PubMedDate not supplied

Pharmacokinetics of ampicillin, sulbactam and cefotiam in patients undergoing orthopedic surgery.

As perioperative prophylaxis for major orthopedic operations 81 patients were given the fixed combination of ampicillin (1 g)/sulbactam (0.5 g) or cefotiam (2 g) as short infusions. The three beta-lactams were rapidly distributed into the different tissues and their pharmacokinetic profiles were found to be very similar. It was noteworthy that ampicillin, sulbactam and cefotiam penetrated within minutes, not only into skin, fat and muscles, but also into bone. Thus 0.25 h after starting the infusion the following mean concentrations were measured in bone: 21.8 +/- 10.5 mg/kg ampicillin, 4.9 +/- 2.2 mg/kg sulbactam and 19.4 +/- 10.6 mg/kg cefotiam. For a period of at least 2 h the concentrations measured in serum and in the different tissues affected by the operation (skin, fat, muscle, bone) were above the MICs for pathogens which are involved in postoperative wound infections. On the basis of pharmacokinetic data, ampicillin/sulbactam and cefotiam seem about equally suitable for perioperative prophylaxis in major orthopedic operations.

Adult↗