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Biomedical subjects

G Peterson

Publications and source records attributed to G Peterson.

At least 109 records · Page 6Linked to original sources
PubMed1979

Frostbite: its diagnosis and treatment.

The treatment, diagnosis, and outcome of frostbite victims is by no means an exact science. As this presentation shows, most authors agree that the key to control and treatment of cold injury comes from a reversal of the damage to the microvasculature (19). The methods of diagnosis of the extent of damage are all based on determination of vascular status whether it be tissue or bony structures. Treatment varies widely but rapid rewarming of the affected tissues is by far the most successful treatment to minimize tissue loss. As in the case study presented here, when surgical amputation is necessary, one must take mechanical function into account as well as the line of demarcation in order to give a functional limb for rehabilitation and to prevent the possibility of subjecting the patient to unnecessary repetitive surgical procedures.

Amputation, Surgical↗
PubMed1977

Cd-metallothionein-a test object for dark-field studies of protein structure.

Cadmium-metallothionein contains about six metal atoms per 6,000 molecular weight, reflecting the high proportion of cystein residues in the structure. Because of the strong scattering from probable Cd-S (Cyst)3 complexes, the protein is unambiguously visualized by conventional tilted beam dark-field electronmicroscopy. The projections of the structure correspond to free, aggregated and partially denatured forms of the presumed native structure, a hexahedral mass, 36 multiplied by 25 multiplied by 16 A. Relaxed states of this structure show that the molecule is comprised of two similar, covalently linked "half-metallothineins", each comprised of three domains. Each of the six domains of the native structure is evidently formed by stacking of two characteristic scattering centers together, at a separation of 9 A. A speculative scheme for the folding of the native structure is presented. The results are interpreted as substantiating the fidelity of dark-field images of small proteins, and the cadmium-metallothionein molecule is suggested as a standard test object for the method.

Animals↗
PubMed1977

The SOAP revolution.

Explore the source record for details and available documents.

Medical Records, Problem-Oriented↗
PubMedDate not supplied

Growth and metabolism in the embryonic white-spotted bamboo shark, Chiloscyllium plagiosum: comparison with embryonic birds and reptiles.

Birds and reptiles have been important models for studying the energetics of embryonic development. Studies on these groups reveal three metabolic patterns: an exponential increase in metabolism with embryo age, a sigmoidal increase with age, or a sigmoidal increase followed by a decrease before hatching. Models developed to explain avian metabolic patterns and developmental costs partition total costs between growth and maintenance. To test the generality of these models, we examined embryonic energetics of the oviparous white-spotted bamboo shark Chiloscyllium plagiosum. Oviparous sharks must actively ventilate during development, which could increase their development costs relative to birds and reptiles. Our results demonstrated that bamboo shark embryos have a peaked metabolic pattern and sigmoidal increase in body mass similar to ratites, crocodilians, and some turtles. The total cost of development was higher in bamboo sharks than in reptiles and many birds. However, calculations reveal that the high cost of bamboo shark development can be explained by the relatively long incubation time rather than the additional cost of muscular movement. Finally, an avian model can reasonably describe shark embryonic metabolism, suggesting that movement costs do not significantly alter the metabolic pattern during development.

Animals↗