Biomedical subjects

G Pasero

Publications and source records attributed to G Pasero.

129 records · Page 8Linked to original sources

PubMedDate not supplied

The treatment of rheumatoid arthritis in this century: from spas to monoclonal antibodies.

In this paper I review the advances in the treatment of rheumatoid arthritis that have taken place in this century. From spas to monoclonal antibodies for the manipulation of the immune system, we have come a long way in just one hundred years. However, although research is being pursued in many promising directions, the discovery of a truly effective treatment for rheumatoid arthritis is still being awaited.

Antibodies, Monoclonal↗

PubMedDate not supplied

Effects of cyclosporin on joint damage in rheumatoid arthritis. The Italian Rheumatologists Study Group on Rheumatoid Arthritis.

According to the most recent literature, few antirheumatic drugs can claim disease-controlling properties over the anatomical joint damage in rheumatoid arthritis (RA). A small number of studies have favored one or another of the available agents, in particular parenteral gold salts, sulphasalazine and methotrexate, but the evidence regarding their efficacy is not convincing when analysed using methodological criteria known to be important in evaluating radiologic evidence of joint damage. The radiologic results in long-standing RA patients have shown that CsA may be of benefit in reducing disease progression. Data from the second year of a clinical trial designed to compare the disease-controlling, anti-rheumatic properties of CsA with those of conventional disease-modifying anti-rheumatic drugs (DMARDs) in early RA support the hypothesis that CsA may be useful in delaying the appearance of new joint erosion.

Adult↗

PubMedDate not supplied

Severe urinary bladder involvement in systemic sclerosis. Case report and review of the literature.

Lower urinary tract involvement is an uncommon manifestation of systemic sclerosis; however, it may represent a troublesome disturbance affecting the quality of life in systemic sclerosis patients. Here we report the case of a middle-aged woman with a 5-year history of systemic sclerosis, who developed severe and progressive urinary bladder sclerosis. This report is particularly interesting because of the severity of the bladder involvement, which required surgical treatment.

Female↗