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Biomedical subjects

G Pandey

Publications and source records attributed to G Pandey.

28 records · Page 2Linked to original sources

Lithium ratio in psychiatric patients: a caveat.

We divided bipolar patient samples into two groups: Group I (off lithium 10 days to 2 weeks, n = 14) and group II (off lithium 3 weeks or longer, n = 13). Only group I was significantly different from controls. The mean for group II was significantly different from that for group I but not that for controls. Previous reports may have exaggerated the number of "high ratio" patients due to a treatment artifact. We recommend that patients be tested only after having been withdrawn from lithium treatment for 3 weeks or more. Otherwise spurious differences between patients and controls may result.

Bipolar Disorder↗

A neuroendocrine study of supersensitivity in tardive dyskinesia.

A study of the tuberoinfundibular dopamine tract was undertaken in chronic schizophrenic patients with and without tardive dyskinesia. Biochemical evidence of the purported dopamine receptor supersensitivity in tardive dyskinesia was sought by demonstrating a hyperresponse of growth hormone and prolactin to dopamine agonists. Contrary to this prediction, no endocrine supersensitivity occurred in the tardive dyskinesia patients. Rather, a significantly decreased response to dopaminergic stimulation was demonstrated in the total chronic schizophrenic group.

Adult↗