Although several attempts at the immunohistochemical characterization of histiocytosis have recently been made there is only one paper which reports a case of cerebral Langerhans cell histiocytosis (LCH) diagnosed by biopsy. This paper presents a bioptically diagnosed case of juvenile histiocytosis. The panel of antibodies used was as follows: anti-S-100, 2 different antibodies to anti-interleukin 2, anti-lysozyme, anti-LEU M1, anti-MAC 387, anti-major histocompatibility complex II and anti-GFAP. Microglia markers--Griffonia simplicifolia and RCA 1 lectins were also utilized. The proliferating cells produced a positive response to S-100, lysozyme and a partially positive response to HLA DR, but responded negatively to MAC 387, LEU M1, lectins, IL2R and GFAP. Our results were compared and analyzed in the light of those obtained by other authors.

Adolescent↗

PubMedDate not supplied

[Recent acquisitions on the leukodystrophies].

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Brain↗

PubMedDate not supplied

[Pathobiology of deficiencies of the nervous system: apropos of cobalt and copper metalloprotein deficiency].

The Author debate a new concept and classification of neurologic nutritional disorders, according with pathobiological data. Cobalt and copper nutritional syndroms are exposed.

Cobalt↗

PubMedDate not supplied

[Pharmacological, electronmicroscopic and histochemical study on an in-vivo model of the dopaminergic nervous system (Dugesia gonocephala s.l)].

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Animals↗

PubMedDate not supplied

[Case of torsion dystonia. Morphological and biochemical study].

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Child↗