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Biomedical subjects

G P Kulakov

Publications and source records attributed to G P Kulakov.

At least 19 recordsLinked to original sources
PubMed1988

[Urea balance in the treatment of acute renal failure by hemofiltration].

Hemofiltration efficacy was assessed in 14 patients with acute renal insufficiency. Purification quality was controlled by the balance of urea as a marker of low molecular mass substances. Ten patients survived. Adequate purification could be attained with the help of hemofiltration disregarding the level of azotemia and catabolism. An indispensible condition for effective treatment was the substitution of an adequate volume of body fluid (approximately 1.2 volume). The effectiveness of the method could be enhanced as many patients tolerated filtration at rate of 200 ml/min and more. A substitution solution was adequately saturated with urea and purification efficacy corresponded to the rate of filtration. In prolonged anuria filtration procedures not less than 2 times a week were considered optimum.

Acute Kidney Injury↗
PubMed1986

[Comparative evaluation of the effectiveness of plasmapheresis and lymphocytoplasmapheresis in the combined treatment of rheumatoid arthritis].

The authors compared 2 methods of apheresis: plasmapheresis (PA) and lymphocytoplasmapheresis (LPA) in 24 patients with rheumatoid arthritis (RA). Both methods were shown to produce a positive effect on a course of rheumatoid process decreasing clinical and laboratory parameters of its activity, improving articular function. Under LPA influence the production of autoantibodies by B-lymphocytes was significantly lowered. PA and LPA were characterized by a more rapid development of the regression of RA symptoms as compared to drug therapy and by a good tolerance of the procedures. On the basis of the results obtained a preliminary conclusion has been made of the greater efficacy of LPA as compared to that of PA. However, the assessment of long-term therapeutic results is required to consider the probable LPA influence on cellular immunity.

Aged↗
PubMed1985

[Isolated ultrafiltration in treating chronic heart failure].

Twenty-five patients with chronic heart failure resistant to drug therapy were subjected to isolated ultrafiltration (IUF) as part of the complex of therapeutic measures. Altogether 76 IUF sessions were made. The results of the use of IUF were controlled by the clinical observation, laboratory studies and ultrasonic exploration of the internal organs. It has been shown that IUF should be included into the complex of therapeutic measures for chronic heart failure.

Adult↗
PubMed1985

[A method of plasmapheresis in patients with hereditary hypercholesterolemia].

The authors describe a procedure of plasmapheresis with plasma ultrafiltration and the ultrafiltrate return to the patient. It has been shown that application of such a procedure of plasmapheresis permits eliminating lipids, with preservation of electrolytes, enzymes, amino acids, vitamins and other valuable plasma components.

Cell Separation↗
PubMed1983

[Acute kidney failure and its treatment using hemodialysis].

Commonly the pathogenesis of acute renal failure (ARF) in the first place takes into consideration acute circulatory and acute toxic nephropathies. But disturbances in humoral regulations are important as well. Compensatory-adaptional reactions of the kidney answering the tubular lesion are causing increasing serum levels of renin, serotonin and histamin accompanied by a consecutive decrease of the diaminoxidase-activity, the latter as the hormone inactivating histamin. The results obtained form trials due to the dynamic behaviour of serotonin, histamin and diaminoxidase in the serum and urine respectively of 17 healthy persons (control), of 17 women with an ARF after abortation and of 5 patients with ARF from complications during pregnancy are reported. Rational managment of ARF should purchase an improvement in renal perfusion, the correction of metabolic deviation--among others--an increase of the diaminoxidase-activity.

Acute Kidney Injury↗
PubMed1982

[Circulatory failure in chronic glomerulo- and pyelonephritis].

The frequency and degree of circulatory insufficiency depending on the stage of the disease are analyzed in 404 patients with chronic glomerulonephritis and 145 patients with chronic pyelonephritis aged 15 to 74 years. When the renal function is still preserved different degrees of circulatory insufficiency are diagnosed in 29.4% of patients. Circulatory insufficiency complicates more often chronic glomerulonephritis than pyelonephritis and is more common in the aged. Latent cardiac insufficiency is more common. In the period of chronic renal insufficiency cardiac decompensation is seen in 78.1% of cases, its frequency is practically the same in glomerulonephritis and pyelonephritis. The mechanisms of development of cardiac insufficiency and the principles of treatment depending on the functional state of the kidneys are discussed.

Adolescent↗