Search PubMed⌕ Search

Biomedical subjects

G P Graham

Publications and source records attributed to G P Graham.

26 records · Page 2Linked to original sources
PubMed1986

Primary oat cell carcinoma of the oesophagus.

Three cases of oat cell carcinoma of the oesophagus are presented and published reports reviewed. This is mainly a disease of older age with a 3:2 predominance of men. Of all published cases, 43 (47.3%) occurred in the middle third, 41 (45.1%) in the lower third, and four (4.4%) in the upper third. In one case it was multifocal and in two the location was not stated. Dysphagia was the most common symptom and was found in 82.5% of cases. Overall survival was 4.7 months. The longest survival in a patient treated by resection was 24 months and in a patient treated by chemotherapy 11 months. All but one of the patients had widely disseminated metastatic disease at death. It is concluded that surgery, possibly with adjuvant chemotherapy, holds out the best prospect for such patients.

Aged↗
PubMed1979

Reliability of electromyographic measurements after surface electrode removal and replacement.

The purpose of this study was to determine the reliability of electromyographic measurements after surface electrode removal and replacement. Eight male subjects performed an isometric exercise with the left triceps brachii at loads equivalent to 50, 40, and 30% of their maximum voluntary contractile strength (MVC). Surface electrodes were utilized and the integrated action potentials recorded electromyographically as the muscle contracted. The muscle was tested first in a rested condition and then again after a sustained 30% maximum voluntary contraction. Each one of the subjects was tested three different times with a range of from 2 to 16 days between testing sessions. The electrodes were removed after each testing session. The data were means in centimeters of integrated action potentials over specified time periods. The test-retest correlations for the three testing periods resulted in coefficients ranging from .87 to .99. This was true under all loads and with the muscle either rested or fatigued.

Adult↗
PubMedDate not supplied

Late knee problems in myelomeningocele.

This study was undertaken to assess the incidence and etiology of knee problems in a long-term follow-up of myelomeningocele patients. Of the 72 community ambulators reviewed, 17 (24%) had significant knee symptoms. A specific gait pattern was identified in symptomatic patients with low lumbar lesions, which may be explained on the basis of hip abductor and calf muscle weakness. These patients have a characteristic gait, which places abnormal stress on the knee, leading to medial and anteromedial rotary instability and eventual degenerative change. It is likely that disability resulting from knee symptoms will be the factor precluding independent ambulation in the patients reviewed in this study.

Adult↗