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Biomedical subjects

G Owen

Publications and source records attributed to G Owen.

At least 73 records · Page 4Linked to original sources
PubMed1989

Tympanic membrane perforation following the removal of ventilation tubes in the presence of persistent aural discharge.

This study considers the effect of the removal of a ventilation tube from the tympanic membrane of an ear which has been affected with persistent mucopurulent discharge for at least 3 months. The records of 332 patients were reviewed. Thirty-three patients with 34 ears satisfied the entry criteria. Tube removal cured 27 out of 34 ears (79%) of aural discharge within 1 month. The tympanic membrane healing rates were: at 1 month, 14 (41%); at 3 months, 23 (68%); at 6 months, 24 (71%); and at 1 year, 28 (82%). A table is presented comparing perforation rates from different ventilation tube studies.

Adolescent↗
PubMed1987

Application of game theoretic analysis to a problem in demography.

"Governments in certain countries have tried over the last two decades to draw most industry to the largest cities. The effect has generally been a large increase in both the population and land area of the cities, as the nearby rural areas are taken out of agricultural production and urbanized. Where the land is especially fertile, this can represent a definite loss to the country's agricultural capabilities. By studying the Nash equilibria we show that, given political pressures, there is a very real danger that this process will continue until all, or practically all of the land has been urbanized." The geographical focus is on Colombia.

Agriculture↗
PubMed1986

Morphology of physiologically identified bipolar cells in the retina of the tiger salamander, Ambystoma tigrinum.

Intracellular recordings of the light responses of bipolar cells were made in the isolated perfused retina of the larval tiger salamander by microelectrodes filled with a 1% solution of the enzyme horseradish peroxidase (HRP). Two classes of bipolar cell were identified in terms of their responses to luminous spots and annuli centered upon their receptive fields: on-center cells, which depolarized in response to a centered spot and hyperpolarized in response to a concentric annulus, and off-center cells, which responded with the opposite polarities. Physiologically identified cells were labelled with HRP by iontophoretic injection and prepared for light microscopy. Examples of each of the three classes of bipolar cell described in Cajal's study of the amphibian retina were found amongst the labelled cells. The only morphological feature found to correlate with the physiological classification was the stratum at which the axon of the cell arborized in the inner plexiform layer. The axons of on-center cells arborized in the more proximal sublamina b, while those of off-center cells arborized in the more distal sublamina a. This is consistent with earlier findings in the retinae of the cat and the carp.

Ambystoma↗
PubMed1984

Water purification and the incidence of fractures in patients receiving home haemodialysis supervised by a single centre: evidence for "safe" upper limit of aluminium in water.

Between 1968 and 1980 fractures occurred in 56 of 284 patients treated by home haemodialysis in the Sheffield area for longer than one year. Patients sustained four times as many fractures while using dialysate prepared with water containing more than 1.0 mumol aluminium per 1 (2.7 micrograms/100 ml) than while using water containing a smaller concentration. When aluminium was removed from water by deionisation the incidence of fractures diminished during the next year and no patient developed dialysis encephalopathy. These findings show that 1.0 mumol/l is a safe maximum concentration of aluminium in water for use in home haemodialysis. It can be detected by the colorimetric aluminium analyses used by many water authorities. When financial resources are limited it is expedient to reserve aluminium analyses by electrothermal atomic absorption for plasma from patients receiving regular haemodialysis. Ingestion of aluminium hydroxide contributes significantly to the increased plasma aluminium concentration of these patients.

Aluminum↗
PubMed1981

The epidemiology and geographical distribution of trachoma in Lebowa.

The prevalence of active trachoma and its potentially blinding sequelae have been estimated in ten settlements scattered throughout rural Lebowa. The disease represents a major public health problem only in northern Lebowa where 25% of subjects over 60 years of age were found to be suffering form visual disability as a result of the infection. Although the disease is endemic in most other parts of lebowa it rarely causes blindness and impaired vision. A rational approach to the control of trachoma in the area which takes into account both local considerations and recent advances in the knowledge of the epidemiology of the disease is recommended.

Adolescent↗
PubMed1981

Suggested sex and age appropriate values for "low" and "deficient" hemoglobin levels.

New values for "deficient" and "low" Hb have been calculated as the smoothed 5th and the 15th percentiles for white males and females included in the National Health and Nutrition Examination Survey (NHANES I). With separate tabulations for 18.389 white individuals contained in this data base and for 12,320 with transferrin saturation values of 16% and above, these new values have the advantage of being fully age-specific, based upon a single source of hematological data and providing quantitative definitions of "low" and "deficient."

Adolescent↗
PubMed1979

Community experience.

Explore the source record for details and available documents.

Community Health Nursing↗
PubMed1977

Paget's disease of bone (osteitis deformans) treated with human synthetic calcitonin.

Thirteen patients with symptoms of active Paget's disease of bone, confirmed biochemically and radiologically, were studied. Each patient received a 6 months' course of therapy with human synthetic calcitonin (HCT), starting with 1 mg daily subcutaneously or intramuscularly for the first month and thereafter 3 times per week for 5 months. Twelve patients completed the course of therapy. Ten of the 12 patients derived moderate to great symptomatic improvement from their treatment. The improvement usually became evident 6 weeks after the start of treatment and this improvement persisted in 4 patients from 6 months to 1 year after treatment was stopped. The plasma alkaline phosphatase had fallen from the initial values by a mean of 26% after 6 weeks and 31% after 6 months of treatment. The urinary hydroxyproline likewise had fallen by 42% at 6 weeks and 46% at 6 months. Side-effects were generally mild and self-limiting, with flushing being the most common. It is concluded that human calcitonin is beneficial in the treatment of Paget's disease of bone and may prevent the problems of antibody resistance and allergic phenomena encountered with other preparations of calcitonin.

Aged↗