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Biomedical subjects

G Ortega

Publications and source records attributed to G Ortega.

At least 73 records · Page 4Linked to original sources
PubMed1991

[Production of monoclonal antibodies against Leishmania mexicana mexicana antigens].

In the present work we obtained three mAbs specific against gp65 of the strain L. mexicana mexicana (NR). These three mAbs were able of recognizing promastigotes of L.m.m. not only for immunofluorescence but also by immunostain. In the immunohistochemistry of biopsies of patients with leishmaniasis, using the three mAbs, it was possible to observe the presence of amastigotes in the infected tissues.

Animals↗
PubMed1991

[Usefulness of captopril as monotherapy and combination therapy in the treatment of arterial hypertension].

The efficacy and tolerance of captopril was prospectively studied as monotherapy for blood hypertension (BH), as well as combined modality with thiazides diuretic and nifedipine as a third drug. 95 cases of BH were followed up for a period of 6 months. 43.15% of the patients who received monotherapy with captopril were controlled (diastolic BP less than 95 mmHg). Those patients who had a diuretic added showed a response of 71.75% and those administered 3 drugs showed a response of 81.25%. The decrease of BH was significant in all groups (p less than 0.01). There was a significant correlation (p less than 0.01) between the response to monotherapy and severity of BH (mild BH 67.50% and severe BH 35.20%). 6.5% of patients abandoned the treatment because of secondary effects. No alterations were noted in the blood test. Monotherapy with captopril is effective in control of mild and moderate BH. In resistant patients, the addition of a diuretic and nifedipine retard as a third drug is useful and well-tolerated in any type of BH severity.

Adult↗
PubMed1991

[Arthritis, endophthalmitis and endocarditis caused by Escherichia coli].

A female diabetic patient of 66 years old with acute pyelonephritis, caused by escherichia coli, was further complicated by bacteremia and a rare septic metastasis such as arthritis of the knee and coxa-femoral, unilateral purulent endophthalmitis with a loss of sight and aortic endocarditis which required a surgical change of valves, the posterior evolution being favourable.

Aged↗
PubMed1991

[Parinaud's oculo-glandular syndrome secondary to cat-scratch disease].

A 56 year old patient with an oculo-glandular syndrome of Parinaud, secondary to a cat scratch disease, is presented. The biopsy of the palpebral conjunctiva and parotid gland showed a non-caseous granulomatosis. The patient met the diagnosis criteria for cat scratch disease and, after treatment with a low dosage of steroids, showed a good evolution.

Cat-Scratch Disease↗
PubMed1991

[Infections and systemic lupus erythematosus. Analysis of risk factors and prognosis. A prospective study (1979-1988)].

We have prospectively studied 48 patients previously diagnosed of systemic lupus erythematosus over a mean follow up period of 5.8 years of which 28 presented 36 episodes of infection and 20 did not develop infections. Urinary infections were the most frequent kind of infection followed by pneumonia and bacteriemia; the most frequently isolated microorganism responsible for those infections were E. colii, staphylococcus aureu and P. mirabillis. We have found a risk factors that and impared renal function an steroid treatment over 20 mg/day were significantly associated with a increasing number of infectious precesses. On the contrary, we have observed that only a bad and critical clinical situation had prognostic value and was significantly associated with an increased mortality.

Adult↗