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Biomedical subjects

G Orlandi

Publications and source records attributed to G Orlandi.

65 records · Page 4Linked to original sources
PubMedDate not supplied

Spontaneous arteriovenous fistula of the vertebral artery. Three case reports.

Three cases of spontaneous arteriovenous fistulas of the vertebral artery (VAF) are reported. In one case the only symptom was a cervical bruit; in the other two cases, symptoms of multiple cervical radiculopathy were also observed. Definitive diagnostic findings were obtained by Doppler ultrasonography, computed tomography, magnetic resonance imaging, and angiography. Clinical signs of radiculopathy disappeared after endovascular balloon occlusion of the fistula, in about 1 month. In one case the vertebral artery was occluded without clinical consequences.

Arteriovenous Fistula↗
PubMedDate not supplied

[Endobronchial administration of netilmicin in patients with bronchopulmonary infections seen in the neurosurgical intensive care unit].

The Authors report the results obtained in the treatment of bronchopulmonary infections in patients hospitalized in the Neurosurgical Intensive Care Unit. Netilmicin was administered by systemic and endobronchial routes. The cleaning of the bronchial tree was always performed. Twenty-six patients (16 males and 10 females) were enrolled and assigned to one of the following groups. Group A: 16 patients with confirmed pneumonia; Group B: 10 patients without bronchopulmonary infections, as controls for serum pharmacokinetic study. In the majority of the cases pneumonia was caused by Staphylococcus aureus and Pseudomonas aeruginosa. The results obtained were positive: pneumonia resolution was observed in 10 patients (67%), improvement in 4 (27%) and failure in one case (6%). A pharmacokinetic study has confirmed bacteriologically active serum levels of netilmicin and also the availability of netilmicin within the bronchial secretions. Endobronchial plus systemic netilmicin administration was active and well tolerated in these critical patients.

Bronchi↗
PubMedDate not supplied

[Echocardiographic and polycardiographic findings in multiple-transfused patients with thalassemia major].

Echocardiographic and policardiographic measurements were carried out in 11 thalassemic major patients between 2 and 24 years of age, kept at on average Hb level of 9,77 gr.% (+/- 1,13) and who underwent chelation therapy with Deferoxamine subcutaneous and Vit. C. The echocardiographic examination gave normal values in 7 patients. In 4 patients underwent enlargement of the left ventricle: only in the telediastolic diameter in one case, with progressive involvement of the aorta and the left atrium in another 3 cases. Such alterations, as have already been recorded by various researchers, are probably the result of a condition due to the anemia state of the younger patients, whereas in older and polytransfused patients may be attributed to iron overload. No parameters surveyed by the polycardiographic examination indicated significant alterations in cardiac efficiency, except of one patient. The importance of echocardiography should be stressed; it is a simple, non invasive way of recording early cardiac alterations in thalassemic major patients and enables long-term monitoring of cardiac function in the assessment of the effectiveness of the chelation therapy.

Adolescent↗