[Cardiovascular effects of hemodialysis. Post-dialytic changes in systolic time intervals].
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Biomedical subjects
Publications and source records attributed to G Oreto.
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The authors report on two cases of ventricular fibrillation induced by bolus of atropine injected for diagnostic purpose. The electrophysiologic effect of adrenergic stimulation following the parasympathetic blockade, is probably the responsible mechanism rather than myocardial ischemia in the first patient, affected by complete a-v block with narrow QRS. The second patient, affected by coronary heart disease and suspected sick sinus syndrome, had more probably a ventricular fibrillation because of a worsening of the underlying myocardial ischemia due to the increase of the cardiac rate. the reported observations, together with those of other Authors, suggest that atropine, at least when used for diagnostic purpose, should be employed cautiously and preferably having available all the equipment for emergency treatment of cardiorespiratory arrest.
A case of attempted suicide with 2600 mg amiodarone is reported. This overdose did not cause any clinical symptoms, change in heart rate, blood pressure or biochemical parameters. No ventricular arrhythmias were observed in ECG monitoring, but a considerable lengthening of the Q-T interval and T wave inversion in the precordial leads with transient disappearance of the R wave in leads V1 - V4, simulating an anteroseptal infarction, were recorded. This case underlines the possibility of giving larger loading doses of amiodarone than those generally used.
This research was done in order to quantify the sinus arrhythmia and to determine any possible quantitative difference between normal subjects and patients with Sick Sinus Syndrome (SSS). The ECG of 200 normal subjects and 30 patients with SSS diagnosed with electrophysiologic evaluation have been studied. 50 consecutive PP intervals have been measured in each ECG, and the average and standard deviation (SD) were calculated. The variableness of the sinus cycle was expressed by the Sinus Arrhythmia Index (SAI), obtained by the ratio between the SD and the average length of the cycle. It was observed that in normal subjects the SAI decreases with aging, and its value is not related to the heart rate. The SAI was significantly higher in the patients with SSS than in the normal ones. Since a sinus arrhythmia of high degree may be observed in the SSS, the quantitative evaluation of this arrhythmia, obtained by the index we proposed, may be useful to the detection of this syndrome.
A case of likewise atrial dissociation in a twelve years old patient affected by mucovisclosis with severe respiratory failure is described. The classic criteria of the atrial dissociation were met in the ECG, in which, beside the sinus P waves, low P-like waves, whose rate was 69/m', were present: they did not conduct to the ventricles and were independent from the sinus rhythm. Such waves always coincided with the beginning of the inspiration, and disappeared during the apnoea. So they were not believed as being the results of electrical forces of the heart, but artifacts produced by respiratory movements. The diagnostic criteria of the atrial dissociation are discussed on the basis of these observations. the exclusion of artifacts, especially the respiratory ones, and the demonstration, obtained through the intracavitary ECG, that the waves are really produced by the heart, are necessary to diagnoses the arrhythmia. By the application of these diagnostic criteria only one of the cases found in the Literature has been accepted as demonstrative of atrial dissociation due to complete intraatrial block in man.
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Phonocardiographic examination was carried out in 40 patients who had undergone to aortic valve replacement with the Björk-Shiley prothesis. The regular function of the prothesis was evaluated on the basis of the physical, radiological and electrocardiographic data. In the majority of the cases the first sound was slight. The prosthetic closing sound was made of two components (a2, A2) and the opening sound by one or more components (C1, C2, C3). A sistolic aortic murmur was always present, and a diastolic murmur has been found in 20% of the cases.
Premature atrial stimulation was carried out in 32 patients, and for each stimulus the basic cycle (A1A1), test cycle (A1A2), and the return cycle (A2A3) were analyzed. When A2A3 was plotted as the function of A1A2, a biphasic pattern, characterized by a slope phase followed by a "plateau", was observed in 25 subjects. Sinoatrial conduction time (SACT) was calculated using the Strauss method, which assumes that in the plateau A2A3 = A1A1 + SACT. Sinus arrhythmia was also determined in order to evaluate its importance in altering the results of premature atrial stimulation: it should be pointed out that when arrhythmia was marked it was impossible to calculate sinoatrial conduction time. An inverse correlation between A1A1 and the calculated SACT and between A1A1 and A2A3/A1A1 in the plateau was also demonstrated. The reliability of SACT obtained by premature atrial stimulation is discussed in relation to the results obtained and the data found in the literature.
42 patients who had undergone aortic valve replacement with the Lillehei-Kaster prosthesis were studied. Phonocardiographic and physical examinations were carried out on these patients to determine the typical auscultatory pattern of this prosthesis. In the majority of the cases, the first sound was slight. The second sound was made up of two components, both produced by the artificial valve. A prosthetic opening sound was also detected. Moreover, a sistolic ejection murmur was present in all of the patients, and a diastolic murmur in 25%.
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This article reports an example of right bundle branch block occurring on alternate beats in the presence of atrial tachycardia with 2:1 atrioventricular conduction. Analysis of the tracing suggests that the alternate disappearance of right bundle branch block is a manifestation of supernormal bundle branch conduction. The phenomenon is assumed to be caused by retrograde concealed conduction within the bundle branch that is blocked in anterograde direction (the "linking" mechanism).
OBJECTIVE: To evaluate the prevalence of atrial septal aneurysm in patients with migraine. BACKGROUND: Migraine has long been considered a risk factor for stroke. Atrial septal aneurysm is often observed in young patients with ischemic stroke and is frequently associated with other conditions potentially leading to embolism. METHODS: We performed a transthoracic echocardiogram in 90 consecutive patients (65 women and 25 men; mean age, 35.3 years [standard deviation, 9]) with migraine but free from cerebral and cardiovascular disease and in 53 control subjects (37 women and 16 men; mean age, 34 years [standard deviation, 10]). The diagnosis of atrial septal aneurysm was performed according to Olivares-Reyes criteria. A transesophageal echocardiogram also was performed in 75 patients with migraine (83.3%). RESULTS: The prevalence of isolated atrial septal aneurysm was higher in patients with migraine with aura (28.5%) than in patients with migraine without aura (3.6%) (P <.005) or in control subjects (1.9%) (P <.005). CONCLUSIONS: Our data suggest a role of atrial septal aneurysm in the genesis of aura in patients with migraine.
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