The kinetics of glycerol and dimethyl sulfoxide in cultured leukemic and Burkitt lymphoma cells.
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Biomedical subjects
Publications and source records attributed to G Niwayama.
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Analysis of 46 sacroiliac joints removed in toto at random during routine autopsies was undertaken to define the pathologic and radiographic alterations of this joint in middle-aged and elderly patients. Each joint was sectioned, photographed and radiographed and large microscopic slides were prepared. Sacroiliac osteoarthrosis resulted in progressive cartilage degeneration, particularly on the ilial side of the joint, with eventual cartilaginous fusion. Para-articular bony ankylosis was produced by bridging osteophytes on the anterior and inferior surfaces. Sacroiliac intra-articular bony ankylosis was confined to cadavers with ankylosing spondylitis. In some patients radiographic differentiation of osteoarthrosis and ankylosing spondylitis may require tomography.
The integrity of the plantar muscle compartments of the human foot were studied utilizing radiographic and anatomic techniques in an attempt to determine potential pathways for spread of soft tissue infection. One of three major plantar muscle compartments--medial, intermediate or lateral--in 24 unembalmed cadaveric feet was injected percutaneously under fluoroscopy with radiopaque Methyl-methacrylate using both manual and automatic injection techniques with pressure callibration. Following freezing, specimens were sectioned, radiographed, and dissected or partially macerated. Frequency and patterns of extravasation of contrast material were documented and recorded. The results obtained support the concepts that: a) there are three distinct plantar muscle compartments that are maintained by intermuscular septae; and b) there are potential communicating pathways provided by specific anatomic structures.
Abnormalities of intervertebral discs associated with vertebral metastasis from prostatic carcinoma are described in an investigation utilizing patient and cadaveric material. Radiographic and pathologic findings indicate that discal abnormality in this situation relates to three potential processes: intervertebral disc degeneration (intervertebral osteochondrosis); cartilaginous (Schmorl's) nodes; discal invasion by tumor. In most patients with vertebral metastasis, the adjacent intervertebral disc appears normal, a useful radiographic finding suggesting the presence of tumor rather than infection. Occasional patients with vertebral metastasis demonstrate roentgen abnormalities of the adjacent intervertebral disc indicating the occurrence of one or more of the above processes.
Percutaneous fine-needle aspiration biopsy was performed on pigs with no complications. Pancreatic cells were retrieved in 73% of the biopsies. Thus, percutaneous biopsy with cytologic examination for pancreatic carcinoma can be performed in order to plan for appropriate therapy.
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