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Biomedical subjects

G Nikolic

Publications and source records attributed to G Nikolic.

At least 55 records · Page 3Linked to original sources

Complex trigeminy.

Explore the source record for details and available documents.

Electrocardiography↗

Acute amphetamine cardiomyopathy in a drug addict.

A case of acute left ventricular failure following an intravenous dose of amphetamine is described. The diagnosis was made by right heart catheterization. This is the first description of acute amphetamine cardiomyopathy in the medical literature.

Acute Disease↗

Torsade de pointes and asystole in a child with complete heart block and prolonged QT interval.

Three-year-old girl with eight month history of convulsive syncope due to complete heart block, prolonged QT interval and paroxysms of ventricular tachycardia is described. An episode of torsade de pointes tachycardia followed by asystole was documented. The symptoms and electrocardiographic abnormalities were controlled by pacemaker therapy. The subset of "congenital heart block" patients with prolonged QT interval is at high risk of sudden death and should be regarded as a previously unrecognized form of Romano-Ward syndrome.

Arrhythmias, Cardiac↗

Cimetidine, vasopressin and chronotropic incompetence.

A 59-year-old man with severe variceal bleeding received therapy with intravenously administered vasopressin and cimetidine. Inappropriate bradycardia, sinoatrial and atrioventricular blocks, and terminal bradycardia leading to asystole, occurred during bleeding, with the greatest number of rhythm abnormalities occurring during combined cimetidine and vasopressin therapy. The results of post-mortem examination showed only mild coronary artery disease. The hazards of combined vasopressin and cimetidine therapy are reviewed.

Arrhythmias, Cardiac↗

Self-predicting stress tests. Predischarge modified stress testing after acute myocardial infarction.

The outcome of 50 consecutive modified predischarge exercise tests after acute myocardial infarction was predicted by three independent observers on the basis of ST segment displacement in the resting pretest 12 lead electrocardiograms. The mean predictive accuracy for the three observers was 82% for a positive test defined as additional ST segment depression or elevation greater than or equal to 0.1 mV, and rose to 94% for a positive test defined as additional ST segment depression greater than or equal to 0.1 mV alone. For the majority of patients, the test result was already apparent in the resting 12 lead electrocardiogram.

Adult↗

Sudden death recorded during Holter monitoring.

Six instances of sudden death were recorded by Holter monitoring, which showed ventricular fibrillation in five and a bradyarrhythmia in one. Complex ventricular ectopic activity preceded cardiac arrest in five patients, including the one with the bradyarrhythmic arrest. Two patients with chronic bifascicular block arrested as a result of ventricular fibrillation. Fifteen cases reports from the literature are reviewed. The composite profile includes advanced myocardial disease (present in all cases), complex ventricular ectopic activity, R-on-T initiation of the terminal rhythm except in patients with prolonged QT interval, and variations in cycle length preceeding the onset of ventricular tachycardia or fibrillation. The role of supraventricular mechanisms in sudden death is uncertain.

Aged↗