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Biomedical subjects

G N Lucas

Publications and source records attributed to G N Lucas.

28 records · Page 2Linked to original sources
PubMed1991

A case of homozygous sickle cell disease in Sri Lanka.

An 11 year old Muslim boy with a 2 month history of fever, loss of appetite, pallor and abdominal distension, had hepato-splenomegaly. Haemoglobin electrophoresis showed the presence of haemoglobins S and F, with complete absence of haemoglobin A. The sickling test was positive. Marital consanguinity was present. In both parents, the sickling test was positive and haemoglobin electrophoresis showed the presence of haemoglobins A and S. This is the first report of homozygous sickle cell disease in Sri Lanka.

Anemia, Sickle Cell↗
PubMed1990

Cryptosporidiosis--oocyst shedding and infection in household contacts.

The incidence of cryptosporidiosis in children with acute diarrhoea when compared with age-matched controls was 6.1% in a paediatric unit. Studies were made on eight immunocompetent children with cryptosporidiosis to determine the period of oocyst shedding after cessation of diarrhoea. The majority (75%) shed oocysts for less than ten days after cessation of diarrhoea. There was considerable variation among patients, some eliminating oocysts more quickly than others. This was not related to the severity or duration of diarrhoea. The sucrose floatation technique was found to be more sensitive than direct smear for detecting small numbers of oocysts present at the end of the shedding period. Studies on household contacts showed infection in 43%, which suggests a subclinical infection or a transient carrier state, and confirms the occurrence of person to person transmission.

Animals↗
PubMedDate not supplied

Plant poisoning: a hospital-based study in Sri Lanka.

This is a prospective hospital based study of 148 cases of plant poisoning seen by the author during a 12 year period. All cases were accidental. There were 2 deaths. Some measures to reduce the incidence of plant poisoning in Sri Lanka are listed.

Child↗
PubMedDate not supplied

Neonatal jaundice due to ABO incompatibility in Sri Lankan.

A prospective study was carried out on 101 neonates with jaundice due to ABO incompatibility. The direct Coomb's test was weakly positive in 4 cases. The indirect Coomb's test using the eluate was positive in 8 cases. In the maternal blood either IgG anti-A or anti-B haemolysin was present in high titre in every case. Phototherapy was given when the indirect serum bilirubin level exceeded 9 mg/dl. Exchange transfusion was done-in 39 cases, 9 babies requiring multiple exchanges. There were 2 deaths.

ABO Blood-Group System↗
PubMedDate not supplied

Kerosene oil poisoning in children: a hospital-based prospective study in Sri Lanka.

This is a prospective hospital based study of 526 cases of kerosene oil poisoning seen during a 10 year period. There were 5 cases of deliberate self poisoning and 1 case of attempted homicide. 520 cases were accidental. Pneumonitis occurred in 299 children of whom 253 had vomited after kerosene oil ingestion. There were 3 deaths.

Adrenal Cortex Hormones↗