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Biomedical subjects

G N Burrow

Publications and source records attributed to G N Burrow.

At least 127 records · Page 7Linked to original sources
PubMed1975

Treatment of hyperthyroidism in pregnancy with propylthiouracil and methimazole.

Twenty-one women were studied who had received propylthiouracil or methimazole during 26 pregnancies. Four of the infants had a goiter at birth, and 3 of these had neonatal thyrotoxicosis. In 2 children neonatal thyrotoxicosis was not evident at birth because of maternal antithyroid therapy. Five children had congenital defects. Two mothers were responsible for 4 of the children with abnormalities, and both mothers had been treated with thiourea drugs for long periods, ranging from 7 to 11 years. The majority of children who are exposed to these drugs in utero appear to have no subsequent ill effects. However, prolonged therapy with these agents may be undesirable.

Abnormalities, Drug-Induced↗
PubMed1975

Clinical uses of thyrotropin-releasing hormone.

Knowledge about the physiology of the endocrine glands has been expanded in the past several years. It now appears that the secretion of the various pituitary hormones is conditioned by specific releasing hormones secreted in the hypothalamus. Thyrotropin-releasing hormone conditions the pituitary to release thyroid-stimulating hormone when the serum thyroid hormone concentration falls below a certain level. A radioimmunoassay for TSH helps the physician to distinguish the different etiologies of hypothyroidism, to confirm the diagnosis of "euthyroid" Graves' disease and to evaluate pituitary function.

Humans↗