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Biomedical subjects

G Moscato

Publications and source records attributed to G Moscato.

99 records · Page 6Linked to original sources
PubMedDate not supplied

[Asthma caused by sodium p-toluene-n-chloro-sulfonamide: observations on a clinical case].

We describe the case of a patient exposed to chloramine-T who experienced severe asthmatic symptoms when spraying chloramine-T solutions. The patient used chloramine-T as a sterilising agent in medical facilities. Occupational asthma due to chloramine-T was diagnosed by means of specific bronchial provocation test (occupational type). We stress the risk of exposure to high levels of chloramine-T and the importance of this compound as a cause of occupational asthma.

Asthma↗
PubMedDate not supplied

[Passive smoking: a risk factor in the home environment].

Recent studies of the health effects of air pollution have pointed out the importance of environmental smoke as a pollution source in household. Several studies showed that children or adults living with parents or other adults who smoke have an increased risk of several effects: respiratory illness in children, changes of respiratory function in children and adults, risk of lung cancer and risk of other cancer than lung cancer. A few epidemiological surveys have studied the relationship between passive smoking and lung cancer. The available epidemiological studies (10 case-control studies, and 3 prospective studies) have been identified and the results combined. There was a 35% increase of risk of lung cancer among nonsmokers living with smokers as compared with nonsmokers living with nonsmokers. However, adjustments due to some degree of misclassification of some nonsmokers who may be still exposed to other people's smoke, increased the risk, which was thus estimated as 53%. Furthermore, cancer risk deriving from cumulative household exposures to cigarette smoke was evaluated. Overall cancer risk increased progressively with the number of household members who smoked. These results were observed for both smoking-related cancer and other sites cancer. Finally, although some of these results need to be confirmed, recent views believe that sufficient evidence is provided that breathing other people's tobacco smoke cause health impairment and lung cancer.

Climate↗
PubMedDate not supplied

[Specific bronchostimulation tests in occupational medicine].

A review of the literature about specific bronchial provocation tests in occupational asthma was made. The Authors focus on some problems related to the methods of exposure; furthermore, in separate chapters the bissynosis and the relationship between specific and aspecific hyperresponsivity are dealt with. The Authors conclude that it is necessary a standardization of the methods for the reproducibility of the tests, and, as in aspecific hyperresponsivity, so also the specific responsivity may be quantified in dose-response curves.

Allergens↗
PubMedDate not supplied

Occupational asthma: fate and management after the diagnosis.

The clinical and socio-professional fate of subjects with occupational asthma is not univocal. We re-examined twenty-nine subjects diagnosed in our center as suffering from this disease an average 14 months, SE 1.54 after the diagnosis. At the follow-up examination each patient underwent interview, spirometry and methacholine challenge, 18 patients (group A) had ceased exposure to the sensitizing agent but among them only 7 had been relocated in another area of the plant, the others had resigned or retired. The other patients had not changed workplace, 7 (group B) having had intermittent exposure to the offending agent and 4 (group C) having continued to be exposed daily. At the follow-up examination only 9 patients were asymptomatic, each of them belonging to group A, whereas in the other 9 of the same group symptoms persisted, although reduced. In group B and C all patients were still symptomatic and required pharmacologic treatment. Within group A patients who became asymptomatic had shorter duration of symptoms before diagnosis (12.9 months, SE 6.4 vs 23.9, SE 9.7), higher FEV-1 (96.1, SE 6.7 vs 86.9, SE 5.6) and PD20FEV-1 (1773.4 micrograms, SE 590 vs 730.8, SE 295) at the time of the diagnosis and showed a significant (p < 0.01) increase in FEV-1 (from 96.1, SE 6.2 to 101.6, SE 5.5) and a tendency to decrease in bronchial reactivity to methacholine at the follow-up examination. At the time of the follow-up examination only 5 out of 29 patients (17.2%) had been contacted by the compensation board.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMedDate not supplied

[A new environmental pathology: styrene-induced rhinitis].

We describe the case of a 36 ys aged woman complaining of symptoms of oculorhinitis with itching, occasional dyspnea and laryngeal constriction. The patient related her symptoms with the emission of dusts and steam from a factory in the neighbourhood producing manufactures using polyester resins dissolved in styrene. No bronchospastic response was obtained after challenge with methacoline and ultrasonic nebulization of distilled water, which instead provoked a significant increase of nasal resistance. The inhalation challenge with styrene produced a dual nasal response. To our knowledge this is the first case of non occupational neighbourhood rhinitis provoked by styrene.

Adult↗
PubMedDate not supplied

[Role and significance of information tools in occupational asthma].

Role of education in occupational asthma. Subjects' education, i.e. information and training in the specific topic, has a substantial role in several medical fields and is considered to be the challenge to reach the primary, secondary and tertiary preventive goals. In occupational medicine workers information and training is considered particularly relevant and it has been included in a recent governative law regarding prevention and health care at the workplace. The present short review deals with the role of education in occupational asthma, which at present appears the most frequently compensated occupational lung disease.

Asthma↗