Biomedical subjects
Publications and source records attributed to G Mori.
Although haemorrhoids have been known for centuries, there is still some controversy on the subject. In addition little attention has so far been paid to their appearance in young people. The incidence and aetiopathogenesis of the condition and the correct therapeutic approach are discussed on the basis of personal experience, clinical research and recent additions to the sparse literature on the subject.
10 patients with anal or rectal cancers were given liquid nitrogen cryogenic treatment. In 5 cases the treatment was given prior to abdominoperineal amputation of the rectum. The remaining 5 inoperable cases were given the cryogenic treatment alone, followed, in 3 cases by derivative colostomy. Histological reports on the removed tissues, carried out at different times after the cryogenic treatment, showed the effects of the treatment on the neoplasias and the surrounding tissues and showed the histological equivalent of possible local immunological processes. The thrombosis in the surrounding blood vessels appears to indicate the efficacity of cryogenic therapy in preventing the metastasis of neoplastic cells.
A method is described for the determination of total acid-labile CO2 (TCO2) and intracellular bicarbonate concentration [HCO3-] in skeletal muscle samples. Surgical biopsies obtained from the quadriceps femoris muscle of 24 Wistar male rats were analyzed for acid-labile CO2 and extra and intracellular water, extracellular water was estimated from the muscle chloride content. TCO2 method utilizes a single diffusion step with absorption of extracted CO2 by sulphuric acid into barium hydroxide and subsequent potentiometric determination of muscle CO2 content. The measured total CO2 content in muscle was 12.01 +/- 1.06 mMol/Kg wet weight when the sample weight was kept in terms of 22-110 mg, assuming a normal membrane potential and a muscle pCO2 equal to femoral vein blood pCO2, calculated intracellular bicarbonate concentration was 12.58 +/- 1.08 mEq/1 H2O i.c. (X +/- D.S.) and intracellular pH was 7.03 +/- 0.04 (X +/- D.S.).
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The A. in a review of the outpatient proctologic practice suggest the application of the crioprobe to the piles first and second degree, and to polyps small ones. A pathogenetic hypothesis of this narrowing application is supported on the basis of the unpractible mucosa, affected by 3rd degree piles. Furthermore the N2O employment seems to be unusefull in the treatment of the polyps and a further improvement of the probes is required.
Ultrastructural and biochemical studies on the collagen and elastin fibres of the dermis from a patient with Elastosis perforans serpiginosa are described. Qualitative and quantitative alterations on collagen and elastin are shown, which give some evidence for considering the disease as a connective tissue defect.
This reviews 839 isolated lumbar sympathectomy performed between 1950 and 1975. The patients are stratified by decades and grouped in 3 periods : 1950 to 1959, 1960 to 1969 and 1970 to 1975. In the first period most patients were between 50 and 59 years old; in the last period most were between 60 and 69 years old. At this time direct vascular reconstruction had become more frequent. The approach described by Pearls was used exclusively in the last period. Isolated lumbar sympathectomy yields a symptomatic improvement. Best results are obtined in peripheral and isolated lesions.
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