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Biomedical subjects

G Mora

Publications and source records attributed to G Mora.

115 records · Page 7Linked to original sources
PubMedDate not supplied

[Estimation of the probability of heterozygosity in Duchenne-type progressive muscular dystrophy].

The severe Duchenne type of muscular dystrophy is inherited as an X-linked recessive trait. Approximately two thirds of healthy female heterozygous carriers have a high serum creatine kinase (SCK). A suspected carrier with a normal SCK level therefore, presents an important problem in genetic counselling. Based on Bayesian methods, Emery and Hollyway derived a formula which is applicable when the sporadic case is either the son or brother of a consultant and which also includes information on SCK levels in the consultant and in normal daughters and sisters. The present paper describes the results obtained with use of this formula in 27 families with at least a propositus with Duchenne muscular dystrophy.

Adolescent↗
PubMedDate not supplied

[Hemoglobin S. Apropos of a family].

The present paper describes a homozygote patient for the gene of hemoglobin S. The patient is the first child of non-consanguineous parents. The family study revealed 11 heterozygote subjects for the sickle cell disease.

Anemia, Sickle Cell↗
PubMedDate not supplied

[Use of bone allografts in the surgical repair of tibial plateau fractures].

The number of indications of the allografts is increasing in bone and joint pathology treatment. With this good alternative, it is possible to avoid the morbidity sometimes observed in patients in which autograft is used. We present 6 cases of fractures of the external tibial plateau type B3 (AO classification) treated using bone allograft (a piece of femoral head) as a support of the tibial plateau after to get a proper reduction of the fractures. In all the cases we got good results in the support function of the allograft as in consolidation, with no complication.

Accidents↗
PubMedDate not supplied

[Allografts in extensive spinal arthrodesis].

Surgery of spinal deformities and vertebral tumors often requires extensive arthrodesis, with the difficulty of obtaining sufficient autogenous bone graft (particularly in children and cases of paralytic deformities) and the necessity of a second incision, thus lengthening the operation and eventual increase of the morbidity. We present 52 patients who suffered from vertebral tumours, fractures or spinal deformities and underwent spinal arthrodesis surgery. Femoral head allografts were used as cancellous bone graft to add to the amount obtained from the arthrodesis bed itself (posterior structures). In three occasions, femoral head grafts shaped as a strut were also used as intersomatic bone graft, being implanted via a costotansversectomy. The only complication was the appearance of seromas of spontaneous resorption in the first 15 cases (thereafter repeated cleaning of the bone graft avoided this problem). In our experience, bone grafts facilitate the carrying out of shorter surgical operations but can also avoid having to recourse the further incisions without reducing the possibility of obtaining a successful arthrodesis.

Adolescent↗