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Biomedical subjects

G Molas

Publications and source records attributed to G Molas.

At least 91 records · Page 5Linked to original sources
PubMed1981

[Search of a cytomegalovirus infection during pseudo-membranous colitis. 6 cases (author's transl)].

Six patients with pseudomembranous colitis unrelated to lincomycin or clindamycin treatment were investigated for signs of localised or diffuse cytomegalovirus (CMV) infection. Before the onset of colitis 3 patients had receive prednisone, associated in 2 of them with immunosuppressive drugs. Testing for CMV included rectal mucosa biopsies, culture of blood leucocytes with human embryo diploid fibroblasts in continuous layer and titration of complement-deviating anti-CMV antibodies. Cytomegalic cells with nuclear inclusion bodies were found in the rectal mucosa of 5 patients, 4 of whom also had foci of CMV-infected cells in leucocyte-fibroblast cultures, indicative of viraemia. The fifth patient was not tested for viraemia but developed very high anti-CMV antibodies titers at a later stage. These results show that pseudomembranous colitis that are not due to antibiotics are frequently associated with localised or diffuse CMV infection. Viral invasion of the colon might be encouraged by a state of immunodeficiency.

Adult↗
PubMed1981

[Subcapsular haematoma of the spleen as complication of chronic pancreatitis. Contribution of echotomography to the diagnosis in two cases (author's transl)].

Two men aged 28 and 33 were found to have subcapsular haematoma of the spleen secondary to chronic alcoholic pancreatitis. One of the patients presented with a pancreatic pseudo-cyst, left amylase pleural effusion and thrombosis of the splenic vein. Selective coeliac and mesenteric angiography and, chiefly, echotomography pointed to the diagnosis, which was confirmed on abdominal incision and histopathological study of the lesions. From these two cases and a review of 63 cases previously published the authors describe the clinical symptoms (acute anaemia with abdominal tumour), pathogeny (vascular or enzymatic) and diagnosis of the condition. Echotomography of the pancreas seems to be the best non invasive method to detect splenic complications of chronic pancreatitis.

Adult↗
PubMed1981

Superficial oesophageal carcinoma: an oesophageal counterpart of early gastric cancer.

The clinicopathological features of 10 cases of superficial oesophageal carcinoma without lymph node metastasis are reported. Superficial oesophageal carcinoma, an uncommon form of oesophageal cancer, is defined as invasive squamous cell carcinoma confined to the mucosa and submucosa. It includes plaque-like, erosive, papillary and occult types but is not associated with the usual macroscopic features of advanced oesophageal cancer. The main presenting symptom of dysphagia and oesophagitis is a frequently quoted endoscopic diagnosis. Superficial oesophageal carcinoma may be preceded by dysplastic and in situ carcinomatous changes and is probable oesophageal counterpart to early gastric cancer.

Aged↗